Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function

Marta Di Grezia; Pietro Fransvea; Francesco Santullo; Flavio Tirelli; Valeria Fico; Paolo Mirco; Valerio Cozza; Antonio La Greca; Gabriele Sganga

doi:10.1016/j.mehy.2020.109954

Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function

Marta Di Grezia, Pietro Fransvea, Francesco Santullo, Flavio Tirelli, Valeria Fico, Paolo Mirco, Valerio Cozza, Antonio La Greca, Gabriele Sganga

Risultato della ricerca: Contributo in rivista › Articolo in rivista

1 Citazioni (Scopus)

Abstract

COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.

Lingua originale	English
pagine (da-a)	109954-N/A
Rivista	Medical Hypotheses
Volume	144
DOI	https://doi.org/10.1016/j.mehy.2020.109954
Stato di pubblicazione	Pubblicato - 2020

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10.1016/j.mehy.2020.109954

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Di Grezia, M., Fransvea, P., Santullo, F., Tirelli, F., Fico, V., Mirco, P., Cozza, V., La Greca, A., & Sganga, G. (2020). Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function. Medical Hypotheses, 144, 109954-N/A. https://doi.org/10.1016/j.mehy.2020.109954

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abstract = "COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.",

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author = "{Di Grezia}, Marta and Pietro Fransvea and Francesco Santullo and Flavio Tirelli and Valeria Fico and Paolo Mirco and Valerio Cozza and {La Greca}, Antonio and Gabriele Sganga",

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doi = "10.1016/j.mehy.2020.109954",

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Di Grezia, M, Fransvea, P, Santullo, F, Tirelli, F, Fico, V, Mirco, P, Cozza, V, La Greca, A & Sganga, G 2020, 'Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function', Medical Hypotheses, vol. 144, pagg. 109954-N/A. https://doi.org/10.1016/j.mehy.2020.109954

Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function. / Di Grezia, Marta; Fransvea, Pietro; Santullo, Francesco et al.
In: Medical Hypotheses, Vol. 144, 2020, pag. 109954-N/A.

Risultato della ricerca: Contributo in rivista › Articolo in rivista

TY - JOUR

T1 - Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function

AU - Di Grezia, Marta

AU - Fransvea, Pietro

AU - Santullo, Francesco

AU - Tirelli, Flavio

AU - Fico, Valeria

AU - Mirco, Paolo

AU - Cozza, Valerio

AU - La Greca, Antonio

AU - Sganga, Gabriele

PY - 2020

Y1 - 2020

N2 - COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.

AB - COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.

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UR - http://hdl.handle.net/10807/159060

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DO - 10.1016/j.mehy.2020.109954

M3 - Article

SN - 0306-9877

VL - 144

SP - 109954-N/A

JO - Medical Hypotheses

JF - Medical Hypotheses

ER -

Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function

Abstract

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