Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study

Stefania Boccia; Ida Torre; Lidia Santarpia; Carmela Iervolino; Concetta Del Piano; Anna Puggina; Roberta Pastorino; Miroslav Dragic; Rosarita Amore; Tonia Borriello; Raffaele Palladino; Francesca Pennino; Franco Contaldo; Fabrizio Pasanisi

doi:10.1016/j.clnu.2016.09.028

Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study

Stefania Boccia, Ida Torre, Lidia Santarpia, Carmela Iervolino, Concetta Del Piano, Anna Puggina, Roberta Pastorino, Miroslav Dragic, Rosarita Amore, Tonia Borriello, Raffaele Palladino, Francesca Pennino, Franco Contaldo, Fabrizio Pasanisi

University of Naples Federico II

Risultato della ricerca: Contributo in rivista › Articolo in rivista

12 Citazioni (Scopus)

Abstract

Introduction: Intestinal bacterial flora plays a central role in human intestinal health and disease. Short Bowel Syndrome (SBS), a clinical condition deriving from extensive bowel resections, influence intestinal microbiota (IM) composition in order to reach a new metabolic balance. Little is known about IM in adult patients after wide intestinal resections. Material and methods: Fecal samples from 12 SBS patients and 16 controls were analyzed in their microbial profile by using both culture-dependent method and quantitative Real-Time PCR (qRT-PCR). Results: The two methods revealed significant lower concentrations of . Bacteroidetes (p-value = .02), . Firmicutes (p-value = .05), . Bifidobacterium (p-value < .01), and . Methanobrevibacter Smithii (p-value = .04) in SBS patients than controls. Conclusions: The significantly different fecal microbiome in SBS patients compared with healthy controls could open new perspectives on the care of their intestinal functions.

Lingua originale	English
pagine (da-a)	1707-1709
Numero di pagine	3
Rivista	Clinical Nutrition
DOI	https://doi.org/10.1016/j.clnu.2016.09.028
Stato di pubblicazione	Pubblicato - 2017

Keywords

Critical Care and Intensive Care Medicine
Intestinal microbiota
Nutrition and Dietetics
Short Bowel Syndrome

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10.1016/j.clnu.2016.09.028

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Boccia, S., Torre, I., Santarpia, L., Iervolino, C., Del Piano, C., Puggina, A., Pastorino, R., Dragic, M., Amore, R., Borriello, T., Palladino, R., Pennino, F., Contaldo, F., & Pasanisi, F. (2017). Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study. Clinical Nutrition, 1707-1709. https://doi.org/10.1016/j.clnu.2016.09.028

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title = "Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study",

abstract = "Introduction: Intestinal bacterial flora plays a central role in human intestinal health and disease. Short Bowel Syndrome (SBS), a clinical condition deriving from extensive bowel resections, influence intestinal microbiota (IM) composition in order to reach a new metabolic balance. Little is known about IM in adult patients after wide intestinal resections. Material and methods: Fecal samples from 12 SBS patients and 16 controls were analyzed in their microbial profile by using both culture-dependent method and quantitative Real-Time PCR (qRT-PCR). Results: The two methods revealed significant lower concentrations of . Bacteroidetes (p-value = .02), . Firmicutes (p-value = .05), . Bifidobacterium (p-value < .01), and . Methanobrevibacter Smithii (p-value = .04) in SBS patients than controls. Conclusions: The significantly different fecal microbiome in SBS patients compared with healthy controls could open new perspectives on the care of their intestinal functions.",

keywords = "Critical Care and Intensive Care Medicine, Intestinal microbiota, Nutrition and Dietetics, Short Bowel Syndrome, Critical Care and Intensive Care Medicine, Intestinal microbiota, Nutrition and Dietetics, Short Bowel Syndrome",

author = "Stefania Boccia and Ida Torre and Lidia Santarpia and Carmela Iervolino and {Del Piano}, Concetta and Anna Puggina and Roberta Pastorino and Miroslav Dragic and Rosarita Amore and Tonia Borriello and Raffaele Palladino and Francesca Pennino and Franco Contaldo and Fabrizio Pasanisi",

year = "2017",

doi = "10.1016/j.clnu.2016.09.028",

language = "English",

pages = "1707--1709",

journal = "Clinical Nutrition",

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publisher = "Editori indicati : CHURCHILL LIVINGSTONE, JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH, SCOTLAND, MIDLOTHIAN, EH1 3AF Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010",

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Boccia, S, Torre, I, Santarpia, L, Iervolino, C, Del Piano, C, Puggina, A, Pastorino, R, Dragic, M, Amore, R, Borriello, T, Palladino, R, Pennino, F, Contaldo, F & Pasanisi, F 2017, 'Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study', Clinical Nutrition, pagg. 1707-1709. https://doi.org/10.1016/j.clnu.2016.09.028

TY - JOUR

T1 - Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study

AU - Boccia, Stefania

AU - Torre, Ida

AU - Santarpia, Lidia

AU - Iervolino, Carmela

AU - Del Piano, Concetta

AU - Puggina, Anna

AU - Pastorino, Roberta

AU - Dragic, Miroslav

AU - Amore, Rosarita

AU - Borriello, Tonia

AU - Palladino, Raffaele

AU - Pennino, Francesca

AU - Contaldo, Franco

AU - Pasanisi, Fabrizio

PY - 2017

Y1 - 2017

N2 - Introduction: Intestinal bacterial flora plays a central role in human intestinal health and disease. Short Bowel Syndrome (SBS), a clinical condition deriving from extensive bowel resections, influence intestinal microbiota (IM) composition in order to reach a new metabolic balance. Little is known about IM in adult patients after wide intestinal resections. Material and methods: Fecal samples from 12 SBS patients and 16 controls were analyzed in their microbial profile by using both culture-dependent method and quantitative Real-Time PCR (qRT-PCR). Results: The two methods revealed significant lower concentrations of . Bacteroidetes (p-value = .02), . Firmicutes (p-value = .05), . Bifidobacterium (p-value < .01), and . Methanobrevibacter Smithii (p-value = .04) in SBS patients than controls. Conclusions: The significantly different fecal microbiome in SBS patients compared with healthy controls could open new perspectives on the care of their intestinal functions.

AB - Introduction: Intestinal bacterial flora plays a central role in human intestinal health and disease. Short Bowel Syndrome (SBS), a clinical condition deriving from extensive bowel resections, influence intestinal microbiota (IM) composition in order to reach a new metabolic balance. Little is known about IM in adult patients after wide intestinal resections. Material and methods: Fecal samples from 12 SBS patients and 16 controls were analyzed in their microbial profile by using both culture-dependent method and quantitative Real-Time PCR (qRT-PCR). Results: The two methods revealed significant lower concentrations of . Bacteroidetes (p-value = .02), . Firmicutes (p-value = .05), . Bifidobacterium (p-value < .01), and . Methanobrevibacter Smithii (p-value = .04) in SBS patients than controls. Conclusions: The significantly different fecal microbiome in SBS patients compared with healthy controls could open new perspectives on the care of their intestinal functions.

KW - Critical Care and Intensive Care Medicine

KW - Intestinal microbiota

KW - Nutrition and Dietetics

KW - Short Bowel Syndrome

KW - Critical Care and Intensive Care Medicine

KW - Intestinal microbiota

KW - Nutrition and Dietetics

KW - Short Bowel Syndrome

UR - http://hdl.handle.net/10807/92929

UR - http://www.elsevier-international.com/journals/clnu/

U2 - 10.1016/j.clnu.2016.09.028

DO - 10.1016/j.clnu.2016.09.028

M3 - Article

SN - 0261-5614

SP - 1707

EP - 1709

JO - Clinical Nutrition

JF - Clinical Nutrition

ER -

Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study

Abstract

Keywords

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