TY - JOUR
T1 - International consensus statement on the diagnosis and management of phaeochromocytoma and paraganglioma in children and adolescents
AU - Casey, Ruth T
AU - Hendriks, Emile
AU - Deal, Cheri
AU - Waguespack, Steven G
AU - Wiegering, Verena
AU - Redlich, Antje
AU - Akker, Scott
AU - Prasad, Rathi
AU - Fassnacht, Martin
AU - Clifton-Bligh, Roderick
AU - Amar, Laurence
AU - Bornstein, Stefan
AU - Canu, Letizia
AU - Charmandari, Evangelia
AU - Chrisoulidou, Alexandra
AU - Freixes, Maria Currás
AU - de Krijger, Ronald
AU - de Sanctis, Luisa
AU - Fojo, Antonio
AU - Ghia, Amol J
AU - Huebner, Angela
AU - Kosmoliaptsis, Vasilis
AU - Kuhlen, Michaela
AU - Raffaelli, Marco
AU - Lussey-Lepoutre, Charlotte
AU - Marks, Stephen D
AU - Nilubol, Naris
AU - Parasiliti-Caprino, Mirko
AU - Timmers, Henri H J L M
AU - Zietlow, Anna Lena
AU - Robledo, Mercedes
AU - Gimenez-Roqueplo, Anne-Paule
AU - Grossman, Ashley B
AU - Taïeb, David
AU - Maher, Eamonn R
AU - Lenders, Jacques W M
AU - Eisenhofer, Graeme
AU - Jimenez, Camilo
AU - Pacak, Karel
AU - Pamporaki, Christina
PY - 2024
Y1 - 2024
N2 - Phaeochromocytomas and paragangliomas (PPGL) are rare neuroendocrine tumours that arise not only in adulthood but also in childhood and adolescence. Up to 70–80% of childhood PPGL are hereditary, accounting for a higher incidence of metastatic and/or multifocal PPGL in paediatric patients than in adult patients. Key differences in the tumour biology and management, together with rare disease incidence and therapeutic challenges in paediatric compared with adult patients, mandate close expert cross-disciplinary teamwork. Teams should ideally include adult and paediatric endocrinologists, oncologists, cardiologists, surgeons, geneticists, pathologists, radiologists, clinical psychologists and nuclear medicine physicians. Provision of an international Consensus Statement should improve care and outcomes for children and adolescents with these tumours.
AB - Phaeochromocytomas and paragangliomas (PPGL) are rare neuroendocrine tumours that arise not only in adulthood but also in childhood and adolescence. Up to 70–80% of childhood PPGL are hereditary, accounting for a higher incidence of metastatic and/or multifocal PPGL in paediatric patients than in adult patients. Key differences in the tumour biology and management, together with rare disease incidence and therapeutic challenges in paediatric compared with adult patients, mandate close expert cross-disciplinary teamwork. Teams should ideally include adult and paediatric endocrinologists, oncologists, cardiologists, surgeons, geneticists, pathologists, radiologists, clinical psychologists and nuclear medicine physicians. Provision of an international Consensus Statement should improve care and outcomes for children and adolescents with these tumours.
KW - phaeochromocytoma
KW - paraganglioma in children
KW - phaeochromocytoma
KW - paraganglioma in children
UR - https://publicatt.unicatt.it/handle/10807/322361
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85201542262&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85201542262&origin=inward
U2 - 10.1038/s41574-024-01024-5
DO - 10.1038/s41574-024-01024-5
M3 - Meeting Abstract
SN - 1759-5029
VL - 20
SP - 729
EP - 748
JO - Nature Reviews Endocrinology
JF - Nature Reviews Endocrinology
IS - 12
ER -
