Abstract
Over the past few years our understanding of the importance of
adaptive immunity in acute coronary syndromes (ACS) has considerably
increased. Profound abnormalities have been observed in specific subsets of CD4+T cells, including type 1 helper T (Th1) cells,CD4+CD28nullT cells, and naturally occurring regulatory T cells (Treg cells).
Recently a new lineage of CD4+T cells, type 17 helper T (Th17) cells producing the signature cytokines interleukin (IL)-17, IL-21, and IL-22, has been identified. This has fundamentally changed the Th1/Th2 dichotomy paradigm.
| Lingua originale | Inglese |
|---|---|
| pagine (da-a) | 556-559 |
| Numero di pagine | 4 |
| Rivista | European Heart Journal |
| Volume | 34 |
| DOI | |
| Stato di pubblicazione | Pubblicato - 2013 |
OSS delle Nazioni Unite
Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile
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SDG 3 Salute e benessere
Keywords
- Acute Coronary Syndromes
- Atherosclerosis
- Immune system
- Interleukin-17
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