TY - JOUR
T1 - Insulin dynamics in young women with polycystic ovary syndrome and normal glucose tolerance across categories of body mass index
AU - Manco, Melania
AU - Castagneto-Gissey, Lidia
AU - Arrighi, Eugenio
AU - Carnicelli, Annamaria
AU - Brufani, Claudia
AU - Luciano, Rosa
AU - Mingrone, Geltrude
PY - 2014
Y1 - 2014
N2 - Evidence favours insulin resistance and compensatory hyperinsulinemia as the predominant, perhaps primary, defects in polycystic ovary syndrome (PCOS). The aim of the present study was to evaluate insulin metabolism in young women with PCOS but normal glucose tolerance as compared with age, body mass index and insulin resistance-matched controls to answer the question whether women with PCOS hypersecrete insulin in comparison to appropriately insulin resistance-matched controls.
AB - Evidence favours insulin resistance and compensatory hyperinsulinemia as the predominant, perhaps primary, defects in polycystic ovary syndrome (PCOS). The aim of the present study was to evaluate insulin metabolism in young women with PCOS but normal glucose tolerance as compared with age, body mass index and insulin resistance-matched controls to answer the question whether women with PCOS hypersecrete insulin in comparison to appropriately insulin resistance-matched controls.
KW - insulin, polycystic ovary syndrome
KW - insulin, polycystic ovary syndrome
UR - http://hdl.handle.net/10807/64618
U2 - 10.1371/journal.pone.0092995
DO - 10.1371/journal.pone.0092995
M3 - Article
SN - 1932-6203
VL - 9
SP - e92995-e92995
JO - PLoS One
JF - PLoS One
ER -