INI1 immunohistochemical expression in glioblastoma: correlation with MGMT gene promoter methylation status and patient survival

Alessandro Sgambato, Alessandro Maiorana, Elena Zunarelli, Nazzarena Bigiani, Giuliana Sartori, Mario Migaldi, Antonio Maiorana

Risultato della ricerca: Contributo in rivistaArticolo in rivista

8 Citazioni (Scopus)

Abstract

INI1 expression and its correlation with MGMT gene promoter methylation status and follow-up was investigated in 77 surgically removed glioblastomas then treated with radiotherapy (RT) or RT plus temozolomide (TMZ).
Lingua originaleEnglish
pagine (da-a)17-23
Numero di pagine7
RivistaPathology
Volume43
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Adult
  • Aged
  • Chromosomal Proteins, Non-Histone
  • DNA Methylation
  • DNA Modification Methylases
  • DNA Repair Enzymes
  • DNA-Binding Proteins
  • Female
  • Gene Expression
  • Glioblastoma
  • Humans
  • Italy
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Promoter Regions, Genetic
  • Supratentorial Neoplasms
  • Survival Rate
  • Transcription Factors
  • Tumor Markers, Biological
  • Tumor Suppressor Proteins

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