Inhibition of prostate efferent neurotransmission by amikacin

Mario Gardi, F Nigro, E Ragazzi, Emilio Sacco, Andrea Volpe, Angelo Totaro, Francesco Pinto, Pierfrancesco Bassi

Risultato della ricerca: Contributo in rivistaArticolo in rivista


It has been suggested that manipulation of the autonomic nerve supply to the prostate leads to loss of functional and structural integrity of the gland, and that these changes may be useful in treating prostatic diseases. This study investigates the effect of amikacin on prostate efferent neurotransmission in vitro, in both rat and human prostate samples.
Lingua originaleEnglish
pagine (da-a)1330-1335
Numero di pagine6
Stato di pubblicazionePubblicato - 2008


  • Adenosine Triphosphate
  • Aged
  • Amikacin
  • Animals
  • Anti-Bacterial Agents
  • Autonomic Nervous System
  • Carbachol
  • Cholinergic Agonists
  • Dose-Response Relationship, Drug
  • Electric Stimulation
  • Humans
  • Male
  • Muscle Contraction
  • Muscle, Smooth
  • Neurons, Efferent
  • Norepinephrine
  • Prostate
  • Prostatic Hyperplasia
  • Rats
  • Rats, Wistar
  • Serotonin


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