Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092)

Vincenzo Valentini; A De Paoli; Maria Antonietta Gambacorta; Giovanna Mantini; Carlo Ratto; Fabio Maria Vecchio; Brunella Barbaro; R Innocente; Concettina Rossi; G Boz; Maria Cristina Barba; Alessandro Frattegiani; M Lupattelli; Giovanni Doglietto

doi:10.1016/j.ijrobp.2008.01.046

Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092)

Vincenzo Valentini
, A De Paoli
, Maria Antonietta Gambacorta
, Giovanna Mantini
, Carlo Ratto
, Fabio Maria Vecchio
, Brunella Barbaro
, R Innocente
, Concettina Rossi
, G Boz
, Maria Cristina Barba
, Alessandro Frattegiani
, M Lupattelli
, Giovanni Doglietto

Risultato della ricerca: Contributo in rivista › Articolo

53 Citazioni (Scopus)

Abstract

To report the final data of a Phase I and II study (1839IL/0092) on the combination of an anti-epidermal growth factor receptor drug (gefitinib), infusional 5-fluorouracil, and preoperative radiotherapy in locally advanced, resectable rectal cancer.

Lingua originale	Inglese
pagine (da-a)	644-649
Numero di pagine	6
Rivista	International Journal of Radiation Oncology Biology Physics
Volume	72
DOI	https://doi.org/10.1016/j.ijrobp.2008.01.046
Stato di pubblicazione	Pubblicato - 2008

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

SDG 3 Salute e benessere

Keywords

Advanced Rectal Cancer
Preoperative chemioradiotherapy

Accesso al documento

10.1016/j.ijrobp.2008.01.046

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Valentini, V., De Paoli, A., Gambacorta, M. A., Mantini, G., Ratto, C., Vecchio, F. M., Barbaro, B., Innocente, R., Rossi, C., Boz, G., Barba, M. C., Frattegiani, A., Lupattelli, M., & Doglietto, G. (2008). Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092). International Journal of Radiation Oncology Biology Physics, 72, 644-649. https://doi.org/10.1016/j.ijrobp.2008.01.046

@article{f36bbed7b12e4742a15c1939e9fb9664,

title = "Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092)",

abstract = "To report the final data of a Phase I and II study (1839IL/0092) on the combination of an anti-epidermal growth factor receptor drug (gefitinib), infusional 5-fluorouracil, and preoperative radiotherapy in locally advanced, resectable rectal cancer.",

keywords = "Advanced Rectal Cancer, Preoperative chemioradiotherapy, Advanced Rectal Cancer, Preoperative chemioradiotherapy",

author = "Vincenzo Valentini and \{De Paoli\}, A and Gambacorta, \{Maria Antonietta\} and Giovanna Mantini and Carlo Ratto and Vecchio, \{Fabio Maria\} and Brunella Barbaro and R Innocente and Concettina Rossi and G Boz and Barba, \{Maria Cristina\} and Alessandro Frattegiani and M Lupattelli and Giovanni Doglietto",

year = "2008",

doi = "10.1016/j.ijrobp.2008.01.046",

language = "English",

volume = "72",

pages = "644--649",

journal = "International Journal of Radiation Oncology Biology Physics",

issn = "0360-3016",

publisher = "Elsevier Inc.",

}

Valentini, V, De Paoli, A, Gambacorta, MA, Mantini, G, Ratto, C, Vecchio, FM, Barbaro, B, Innocente, R, Rossi, C, Boz, G, Barba, MC, Frattegiani, A, Lupattelli, M & Doglietto, G 2008, 'Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092)', International Journal of Radiation Oncology Biology Physics, vol. 72, pagg. 644-649. https://doi.org/10.1016/j.ijrobp.2008.01.046

Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092). / Valentini, Vincenzo; De Paoli, A; Gambacorta, Maria Antonietta et al.
In: International Journal of Radiation Oncology Biology Physics, Vol. 72, 2008, pag. 644-649.

Risultato della ricerca: Contributo in rivista › Articolo

TY - JOUR

T1 - Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092)

AU - Valentini, Vincenzo

AU - De Paoli, A

AU - Gambacorta, Maria Antonietta

AU - Mantini, Giovanna

AU - Ratto, Carlo

AU - Vecchio, Fabio Maria

AU - Barbaro, Brunella

AU - Innocente, R

AU - Rossi, Concettina

AU - Boz, G

AU - Barba, Maria Cristina

AU - Frattegiani, Alessandro

AU - Lupattelli, M

AU - Doglietto, Giovanni

PY - 2008

Y1 - 2008

N2 - To report the final data of a Phase I and II study (1839IL/0092) on the combination of an anti-epidermal growth factor receptor drug (gefitinib), infusional 5-fluorouracil, and preoperative radiotherapy in locally advanced, resectable rectal cancer.

AB - To report the final data of a Phase I and II study (1839IL/0092) on the combination of an anti-epidermal growth factor receptor drug (gefitinib), infusional 5-fluorouracil, and preoperative radiotherapy in locally advanced, resectable rectal cancer.

KW - Advanced Rectal Cancer

KW - Preoperative chemioradiotherapy

KW - Advanced Rectal Cancer

KW - Preoperative chemioradiotherapy

UR - http://hdl.handle.net/10807/32968

U2 - 10.1016/j.ijrobp.2008.01.046

DO - 10.1016/j.ijrobp.2008.01.046

M3 - Article

SN - 0360-3016

VL - 72

SP - 644

EP - 649

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

ER -

Valentini V, De Paoli A, Gambacorta MA, Mantini G, Ratto C, Vecchio FM et al. Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092). International Journal of Radiation Oncology Biology Physics. 2008;72:644-649. doi: 10.1016/j.ijrobp.2008.01.046

Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092)

Abstract

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Keywords

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