Influence of Biliopancreatic Diversion on Pregnancy Outcomes in Comparison to Other Bariatric Surgery Procedures

Sara De Carolis, Angela Botta, Gelsomina Del Sordo, R. Guerrisi, Silvia Salvi, Maria Pia De Carolis, Amerigo Iaconelli, Piero Giustacchini, Marco Raffaelli, Antonio Lanzone

Risultato della ricerca: Contributo in rivistaArticolo in rivista

6 Citazioni (Scopus)


Background: Pregnancy after bariatric surgery (BS) has an increased risk for small-for-gestational-age infants (SGA), shorter length of gestation, and probably perinatal mortality. The aim of this study was to investigate if biliopancreatic diversion could impair pregnancy outcomes in comparison to other bariatric surgery procedures. Methods: We conducted a cohort retrospective single-center study in 65 women before and after BS. Thirty-one pregnancies occurred before BS, while 109 after BS, amongst which n = 51 after biliopancreatic diversion (BPD) and n = 58 after non-malabsorptive procedures. Results: The pregnancy outcomes after BS in comparison with those before BS resulted less affected by diabetes, hypertensive disorders, macrosomia, and large-for-gestational-age (LGA), but more complicated by preterm births (14.5 versus 4.0%) and low birth weight (LBW) infants (28.9 versus 0%). Moreover, mean birth weight resulted lower after BS than before BS (p < 0.001). In pregnancies after BPD in comparison to those before BS, the LBW rate (42.5%) resulted a drastic increase (p < 0.001), and mean birth weight (p < 0.001) and mean birth weight centile (p < 0.001) were lower after BPD. When pregnancy outcomes after BPD were compared with those after non-malabsorptive procedures, the rate of congenital anomalies, preterm births, LBW, and SGA resulted an increase (p = 0.002, 0.008, 0.032, and < 0.001, respectively). Conclusions: BPD drastically reduced diabetes, hypertensive disorders, macrosomia, and LGA; however, it was associated with the poorest pregnancy outcomes in comparison to those observed after other BS procedures. On the basis of the present study, we recommend a cautious multidisciplinary selection of severely obese patients for BPD during the fertile age.
Lingua originaleEnglish
pagine (da-a)3284-3292
Numero di pagine9
RivistaObesity Surgery
Stato di pubblicazionePubblicato - 2018


  • Bariatric surgery
  • Biliopancreatic diversion
  • Congenital anomalies
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics
  • Obesity
  • Pregnancy outcomes
  • Surgery


Entra nei temi di ricerca di 'Influence of Biliopancreatic Diversion on Pregnancy Outcomes in Comparison to Other Bariatric Surgery Procedures'. Insieme formano una fingerprint unica.

Cita questo