Infections caused by KPC-producing Klebsiella pneumoniae: differences in therapy and mortality in a multicentre study

Mario Tumbarello, Teresa Spanu, Roberto Cauda, Francesco Giuseppe De Rosa, Maddalena Giannella, Daniele Roberto Giacobbe, Matteo Bassetti, Michele Bartoletti, Valerio Del Bono, Silvia Corcione, Sara Tedeschi, Chiara Simona Cardellino, Anna Marchese, Simone Ambretti, Claudio Viscoli, Pierluigi Viale

Risultato della ricerca: Contributo in rivistaArticolo in rivista

316 Citazioni (Scopus)

Abstract

Infections caused by Klebsiella pneumoniae (Kp) carbapenemase (KPC)-producing strains of Kp have become a significant threat in recent years. To assess their outcomes and identify risk factors for 14 day mortality, we conducted a 4 year (2010-13) retrospective cohort study in five large Italian teaching hospitals.
Lingua originaleEnglish
pagine (da-a)2133-2143
Numero di pagine11
RivistaJournal of Antimicrobial Chemotherapy
Volume70
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • carbapenem resistance
  • carbapenemases
  • colistin resistance
  • combination therapy
  • inadequate empirical therapy
  • meropenem MICs
  • treatment

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