Inducing tolerability of adverse events increases sorafenib exposure and optimizes patient's outcome in advanced hepatocellular carcinoma

Risultato della ricerca: Contributo in rivistaArticolo in rivista

16 Citazioni (Scopus)

Abstract

Various grades of adverse events are associated with sorafenib and have recently been considered as a surrogate of response in patients with advanced hepatocellular carcinoma. The aim of this prospective study was to measure the efficacy of a sorafenib dose reduction regimen, adjusted on patient's tolerability, and aimed at increasing the exposure to the drug.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaLiver International
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • adverse events
  • hepatocellular carcinoma
  • sorafenib
  • tolerable adverse events protocol
  • toxicity
  • tumor response

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