Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Luca Reggiani Bonetti; Mario Migaldi; Emanuele Caredda; Alma Boninsegna Lucarelli; Maurizio Ponz De Leon; Carmela Di Gregorio; Valeria Barresi; Domenico Scannone; Silvio Danese; Achille Renato Maria Cittadini; Alessandro Sgambato

doi:10.3109/00365521.2012.694904

Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Luca Reggiani Bonetti
, Mario Migaldi
, Emanuele Caredda
, Alma Boninsegna Lucarelli
, Maurizio Ponz De Leon
, Carmela Di Gregorio
, Valeria Barresi
, Domenico Scannone
, Silvio Danese
, Achille Renato Maria Cittadini
, Alessandro Sgambato

Risultato della ricerca: Contributo in rivista › Articolo

18 Citazioni (Scopus)

Abstract

Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.

Lingua originale	Inglese
pagine (da-a)	1211-1217
Numero di pagine	7
Rivista	Scandinavian Journal of Gastroenterology
Volume	47
DOI	https://doi.org/10.3109/00365521.2012.694904
Stato di pubblicazione	Pubblicato - 2012

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

SDG 3 Salute e benessere

Keywords

CD113
colo-rectal cancer

Accesso al documento

10.3109/00365521.2012.694904

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Reggiani Bonetti, L., Migaldi, M., Caredda, E., Boninsegna Lucarelli, A., Ponz De Leon, M., Di Gregorio, C., Barresi, V., Scannone, D., Danese, S., Cittadini, A. R. M., & Sgambato, A. (2012). Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients. Scandinavian Journal of Gastroenterology, 47, 1211-1217. https://doi.org/10.3109/00365521.2012.694904

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title = "Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients",

abstract = "Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.",

keywords = "CD113, colo-rectal cancer, CD113, colo-rectal cancer",

author = "\{Reggiani Bonetti\}, Luca and Mario Migaldi and Emanuele Caredda and \{Boninsegna Lucarelli\}, Alma and \{Ponz De Leon\}, Maurizio and \{Di Gregorio\}, Carmela and Valeria Barresi and Domenico Scannone and Silvio Danese and Cittadini, \{Achille Renato Maria\} and Alessandro Sgambato",

year = "2012",

doi = "10.3109/00365521.2012.694904",

language = "English",

volume = "47",

pages = "1211--1217",

journal = "Scandinavian Journal of Gastroenterology",

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publisher = "Taylor and Francis Ltd.",

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Reggiani Bonetti, L, Migaldi, M, Caredda, E, Boninsegna Lucarelli, A, Ponz De Leon, M, Di Gregorio, C, Barresi, V, Scannone, D, Danese, S, Cittadini, ARM & Sgambato, A 2012, 'Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients', Scandinavian Journal of Gastroenterology, vol. 47, pagg. 1211-1217. https://doi.org/10.3109/00365521.2012.694904

TY - JOUR

T1 - Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

AU - Reggiani Bonetti, Luca

AU - Migaldi, Mario

AU - Caredda, Emanuele

AU - Boninsegna Lucarelli, Alma

AU - Ponz De Leon, Maurizio

AU - Di Gregorio, Carmela

AU - Barresi, Valeria

AU - Scannone, Domenico

AU - Danese, Silvio

AU - Cittadini, Achille Renato Maria

AU - Sgambato, Alessandro

PY - 2012

Y1 - 2012

N2 - Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.

AB - Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.

KW - CD113

KW - colo-rectal cancer

KW - CD113

KW - colo-rectal cancer

UR - http://hdl.handle.net/10807/40255

U2 - 10.3109/00365521.2012.694904

DO - 10.3109/00365521.2012.694904

M3 - Article

SN - 0036-5521

VL - 47

SP - 1211

EP - 1217

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

ER -

Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Abstract

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Keywords

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