Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Alessandro Sgambato, Emanuele Caredda, Alma Boninsegna Lucarelli, Silvio Danese, Achille Renato Maria Cittadini, Luca Reggiani Bonetti, Mario Migaldi, Maurizio Ponz De Leon, Carmela Di Gregorio, Valeria Barresi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

18 Citazioni (Scopus)

Abstract

Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.
Lingua originaleEnglish
pagine (da-a)1211-1217
Numero di pagine7
RivistaScandinavian Journal of Gastroenterology
Volume47
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • CD113
  • colo-rectal cancer

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