TY - JOUR
T1 - Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients
AU - Reggiani Bonetti, Luca
AU - Migaldi, Mario
AU - Caredda, Emanuele
AU - Boninsegna Lucarelli, Alma
AU - Ponz De Leon, Maurizio
AU - Di Gregorio, Carmela
AU - Barresi, Valeria
AU - Scannone, Domenico
AU - Danese, Silvio
AU - Cittadini, Achille Renato Maria
AU - Sgambato, Alessandro
PY - 2012
Y1 - 2012
N2 - Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.
AB - Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.
KW - CD113
KW - colo-rectal cancer
KW - CD113
KW - colo-rectal cancer
UR - http://hdl.handle.net/10807/40255
U2 - 10.3109/00365521.2012.694904
DO - 10.3109/00365521.2012.694904
M3 - Article
SN - 0036-5521
VL - 47
SP - 1211
EP - 1217
JO - Scandinavian Journal of Gastroenterology
JF - Scandinavian Journal of Gastroenterology
ER -
