Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Luca Reggiani Bonetti; Mario Migaldi; Emanuele Caredda; Alma Boninsegna Lucarelli; Maurizio Ponz De Leon; Carmela Di Gregorio; Valeria Barresi; Domenico Scannone; Silvio Danese; Achille Renato Maria Cittadini; Alessandro Sgambato

doi:10.3109/00365521.2012.694904

Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Luca Reggiani Bonetti, Mario Migaldi, Emanuele Caredda, Alma Boninsegna Lucarelli, Maurizio Ponz De Leon, Carmela Di Gregorio, Valeria Barresi, Domenico Scannone, Silvio Danese, Achille Renato Maria Cittadini, Alessandro Sgambato

Risultato della ricerca: Contributo in rivista › Articolo in rivista

18 Citazioni (Scopus)

Abstract

Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.

Lingua originale	English
pagine (da-a)	1211-1217
Numero di pagine	7
Rivista	Scandinavian Journal of Gastroenterology
Volume	47
DOI	https://doi.org/10.3109/00365521.2012.694904
Stato di pubblicazione	Pubblicato - 2012

Keywords

CD113
colo-rectal cancer

OSS delle Nazioni Unite

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10.3109/00365521.2012.694904

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Reggiani Bonetti, L., Migaldi, M., Caredda, E., Boninsegna Lucarelli, A., Ponz De Leon, M., Di Gregorio, C., Barresi, V., Scannone, D., Danese, S., Cittadini, A. R. M., & Sgambato, A. (2012). Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients. Scandinavian Journal of Gastroenterology, 47, 1211-1217. https://doi.org/10.3109/00365521.2012.694904

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abstract = "Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.",

keywords = "CD113, colo-rectal cancer, CD113, colo-rectal cancer",

author = "{Reggiani Bonetti}, Luca and Mario Migaldi and Emanuele Caredda and {Boninsegna Lucarelli}, Alma and {Ponz De Leon}, Maurizio and {Di Gregorio}, Carmela and Valeria Barresi and Domenico Scannone and Silvio Danese and Cittadini, {Achille Renato Maria} and Alessandro Sgambato",

year = "2012",

doi = "10.3109/00365521.2012.694904",

language = "English",

volume = "47",

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publisher = "Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245",

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Reggiani Bonetti, L, Migaldi, M, Caredda, E, Boninsegna Lucarelli, A, Ponz De Leon, M, Di Gregorio, C, Barresi, V, Scannone, D, Danese, S, Cittadini, ARM & Sgambato, A 2012, 'Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients', Scandinavian Journal of Gastroenterology, vol. 47, pagg. 1211-1217. https://doi.org/10.3109/00365521.2012.694904

TY - JOUR

T1 - Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

AU - Reggiani Bonetti, Luca

AU - Migaldi, Mario

AU - Caredda, Emanuele

AU - Boninsegna Lucarelli, Alma

AU - Ponz De Leon, Maurizio

AU - Di Gregorio, Carmela

AU - Barresi, Valeria

AU - Scannone, Domenico

AU - Danese, Silvio

AU - Cittadini, Achille Renato Maria

AU - Sgambato, Alessandro

PY - 2012

Y1 - 2012

N2 - Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.

AB - Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.

KW - CD113

KW - colo-rectal cancer

KW - CD113

KW - colo-rectal cancer

UR - http://hdl.handle.net/10807/40255

U2 - 10.3109/00365521.2012.694904

DO - 10.3109/00365521.2012.694904

M3 - Article

SN - 0036-5521

VL - 47

SP - 1211

EP - 1217

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

ER -

Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Abstract

Keywords

OSS delle Nazioni Unite

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