Incidental diagnosis and tempestive therapy in a case of neonatal alloimmune thrombocytopenia due to anti-HPA-5b

Antonio Alberto Zuppa; Francesco Cota; Daniele De Luca; Federica Visintini; Pierluigi De Turris; Giuseppe Gio Batta Tortorolo

Incidental diagnosis and tempestive therapy in a case of neonatal alloimmune thrombocytopenia due to anti-HPA-5b

Antonio Alberto Zuppa, Francesco Cota, Daniele De Luca, Federica Visintini, Pierluigi De Turris, Giuseppe Gio Batta Tortorolo

Facoltà di Medicina e Chirurgia "A.Gemelli"

Risultato della ricerca: Contributo in rivista › Articolo in rivista

1 Citazioni (Scopus)

Abstract

Neonatal alloimmune thrombocytopenia (NAIT) is usually attributable to HPA-1a antibodies. The authors report a case of incidentally diagnosed thrombocytopenia in a small for gestational age infant. A NAIT was suspected and she was successfully treated with intravenous IgG. The direct and indirect platelet suspension immunofluorescence test (PSIFT) in maternal blood suggested alloimmunization to HPA-5b. Empiric treatment with IgG could be useful in case of clear suspect even in absence of confirmed diagnosis.

Lingua originale	English
pagine (da-a)	587-591
Numero di pagine	5
Rivista	Pediatric Hematology and Oncology
Stato di pubblicazione	Pubblicato - 2002

Keywords

newborn
thrombocytopenia

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title = "Incidental diagnosis and tempestive therapy in a case of neonatal alloimmune thrombocytopenia due to anti-HPA-5b",

abstract = "Neonatal alloimmune thrombocytopenia (NAIT) is usually attributable to HPA-1a antibodies. The authors report a case of incidentally diagnosed thrombocytopenia in a small for gestational age infant. A NAIT was suspected and she was successfully treated with intravenous IgG. The direct and indirect platelet suspension immunofluorescence test (PSIFT) in maternal blood suggested alloimmunization to HPA-5b. Empiric treatment with IgG could be useful in case of clear suspect even in absence of confirmed diagnosis.",

keywords = "newborn, thrombocytopenia, newborn, thrombocytopenia",

author = "Zuppa, {Antonio Alberto} and Francesco Cota and {De Luca}, Daniele and Federica Visintini and {De Turris}, Pierluigi and Tortorolo, {Giuseppe Gio Batta}",

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Incidental diagnosis and tempestive therapy in a case of neonatal alloimmune thrombocytopenia due to anti-HPA-5b. / Zuppa, Antonio Alberto; Cota, Francesco; De Luca, Daniele; Visintini, Federica; De Turris, Pierluigi; Tortorolo, Giuseppe Gio Batta.

In: Pediatric Hematology and Oncology, 2002, pag. 587-591.

Risultato della ricerca: Contributo in rivista › Articolo in rivista

TY - JOUR

T1 - Incidental diagnosis and tempestive therapy in a case of neonatal alloimmune thrombocytopenia due to anti-HPA-5b

AU - Zuppa, Antonio Alberto

AU - Cota, Francesco

AU - De Luca, Daniele

AU - Visintini, Federica

AU - De Turris, Pierluigi

AU - Tortorolo, Giuseppe Gio Batta

PY - 2002

Y1 - 2002

N2 - Neonatal alloimmune thrombocytopenia (NAIT) is usually attributable to HPA-1a antibodies. The authors report a case of incidentally diagnosed thrombocytopenia in a small for gestational age infant. A NAIT was suspected and she was successfully treated with intravenous IgG. The direct and indirect platelet suspension immunofluorescence test (PSIFT) in maternal blood suggested alloimmunization to HPA-5b. Empiric treatment with IgG could be useful in case of clear suspect even in absence of confirmed diagnosis.

AB - Neonatal alloimmune thrombocytopenia (NAIT) is usually attributable to HPA-1a antibodies. The authors report a case of incidentally diagnosed thrombocytopenia in a small for gestational age infant. A NAIT was suspected and she was successfully treated with intravenous IgG. The direct and indirect platelet suspension immunofluorescence test (PSIFT) in maternal blood suggested alloimmunization to HPA-5b. Empiric treatment with IgG could be useful in case of clear suspect even in absence of confirmed diagnosis.

KW - newborn

KW - thrombocytopenia

KW - newborn

KW - thrombocytopenia

UR - http://hdl.handle.net/10807/16370

M3 - Article

SP - 587

EP - 591

JO - Pediatric Hematology and Oncology

JF - Pediatric Hematology and Oncology

SN - 0888-0018

ER -

Incidental diagnosis and tempestive therapy in a case of neonatal alloimmune thrombocytopenia due to anti-HPA-5b

Abstract

Keywords

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