TY - JOUR
T1 - Incidence, clinical features and management of hypersensitivity reactions to chemotherapeutic drugs in children with cancer
AU - Ruggiero, Antonio
AU - Triarico, Silvia
AU - Trombatore, Giovanna
AU - Battista, Andrea
AU - Dell'Acqua, Fabiola
AU - Rizzari, Carmelo
AU - Riccardi, Riccardo
PY - 2013
Y1 - 2013
N2 - Hypersensitivity reactions (HSRs) may occur in children with cancer during the use of almost all chemotherapeutic drugs. HSRs may also produce a negative impact on treatment intensity and, as a consequence, worsen patients' outcome. The aim of this review is to summarize the incidence and the clinical features of HSRs occurring in children with cancer treated with chemotherapeutic drugs and their impact on treatment efficacy, in order to outline possible adequate prevention and management strategies.
AB - Hypersensitivity reactions (HSRs) may occur in children with cancer during the use of almost all chemotherapeutic drugs. HSRs may also produce a negative impact on treatment intensity and, as a consequence, worsen patients' outcome. The aim of this review is to summarize the incidence and the clinical features of HSRs occurring in children with cancer treated with chemotherapeutic drugs and their impact on treatment efficacy, in order to outline possible adequate prevention and management strategies.
KW - chemotherapeutic drugs
KW - hypersensitivity
KW - chemotherapeutic drugs
KW - hypersensitivity
UR - http://hdl.handle.net/10807/53456
U2 - 10.1007/s00228-013-1546-0
DO - 10.1007/s00228-013-1546-0
M3 - Article
SN - 0031-6970
VL - 69
SP - 1739
EP - 1746
JO - European Journal of Clinical Pharmacology
JF - European Journal of Clinical Pharmacology
ER -