In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias

Vincenzo Di Lazzaro; Fabio Pilato; M. Dileone; E. Saturno; A. Oliviero; Camillo Marra; Antonio Daniele; Federico Ranieri; Guido Gainotti; P. A. Tonali

doi:10.1212/01.wnl.0000204183.26231.23

In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias

Vincenzo Di Lazzaro, Fabio Pilato, M. Dileone, E. Saturno, A. Oliviero, Camillo Marra, Antonio Daniele, Federico Ranieri, Guido Gainotti, P. A. Tonali

Risultato della ricerca: Contributo in rivista › Articolo in rivista

87 Citazioni (Scopus)

Abstract

The test of short latency afferent inhibition (SAI) of the motor cortex is helpful in demonstrating dysfunction of central cholinergic circuits in Alzheimer disease (AD). The authors evaluated SAI in 20 patients with frontotemporal dementia (FTD) and compared data with those from 20 patients with AD and 20 controls. SAI was normal in FTD, whereas it was reduced in AD. SAI may represent an additional tool to discriminate FTD from AD. Copyright © 2006 by AAN Enterprises, Inc.

Lingua originale	English
pagine (da-a)	1111-1113
Numero di pagine	3
Rivista	Neurology
Volume	66
DOI	https://doi.org/10.1212/01.wnl.0000204183.26231.23
Stato di pubblicazione	Pubblicato - 2006

Keywords

Afferent Pathways
Aged
Alzheimer Disease
Cholinesterase Inhibitors
Electrophysiology
Female
Frontal Lobe
Humans
Male
Memory, Short-Term
Middle Aged
Neural Pathways
Reaction Time
Reference Values
Temporal Lobe

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10.1212/01.wnl.0000204183.26231.23

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title = "In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias",

abstract = "The test of short latency afferent inhibition (SAI) of the motor cortex is helpful in demonstrating dysfunction of central cholinergic circuits in Alzheimer disease (AD). The authors evaluated SAI in 20 patients with frontotemporal dementia (FTD) and compared data with those from 20 patients with AD and 20 controls. SAI was normal in FTD, whereas it was reduced in AD. SAI may represent an additional tool to discriminate FTD from AD. Copyright {\textcopyright} 2006 by AAN Enterprises, Inc.",

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doi = "10.1212/01.wnl.0000204183.26231.23",

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T1 - In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias

AU - Di Lazzaro, Vincenzo

AU - Pilato, Fabio

AU - Dileone, M.

AU - Saturno, E.

AU - Oliviero, A.

AU - Marra, Camillo

AU - Daniele, Antonio

AU - Ranieri, Federico

AU - Gainotti, Guido

AU - Tonali, P. A.

PY - 2006

Y1 - 2006

N2 - The test of short latency afferent inhibition (SAI) of the motor cortex is helpful in demonstrating dysfunction of central cholinergic circuits in Alzheimer disease (AD). The authors evaluated SAI in 20 patients with frontotemporal dementia (FTD) and compared data with those from 20 patients with AD and 20 controls. SAI was normal in FTD, whereas it was reduced in AD. SAI may represent an additional tool to discriminate FTD from AD. Copyright © 2006 by AAN Enterprises, Inc.

AB - The test of short latency afferent inhibition (SAI) of the motor cortex is helpful in demonstrating dysfunction of central cholinergic circuits in Alzheimer disease (AD). The authors evaluated SAI in 20 patients with frontotemporal dementia (FTD) and compared data with those from 20 patients with AD and 20 controls. SAI was normal in FTD, whereas it was reduced in AD. SAI may represent an additional tool to discriminate FTD from AD. Copyright © 2006 by AAN Enterprises, Inc.

KW - Afferent Pathways

KW - Aged

KW - Alzheimer Disease

KW - Cholinesterase Inhibitors

KW - Electrophysiology

KW - Female

KW - Frontal Lobe

KW - Humans

KW - Male

KW - Memory, Short-Term

KW - Middle Aged

KW - Neural Pathways

KW - Reaction Time

KW - Reference Values

KW - Temporal Lobe

KW - Afferent Pathways

KW - Aged

KW - Alzheimer Disease

KW - Cholinesterase Inhibitors

KW - Electrophysiology

KW - Female

KW - Frontal Lobe

KW - Humans

KW - Male

KW - Memory, Short-Term

KW - Middle Aged

KW - Neural Pathways

KW - Reaction Time

KW - Reference Values

KW - Temporal Lobe

UR - http://hdl.handle.net/10807/141738

U2 - 10.1212/01.wnl.0000204183.26231.23

DO - 10.1212/01.wnl.0000204183.26231.23

M3 - Article

SN - 0028-3878

VL - 66

SP - 1111

EP - 1113

JO - Neurology

JF - Neurology

ER -

In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias

Abstract

Keywords

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