In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

Barbara Fiori; Brunella Posteraro; Riccardo Torelli; Mario Tumbarello; David S. Perlin; Giovanni Fadda; Maurizio Sanguinetti

doi:10.1128/AAC.01569-10

In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

Barbara Fiori
, Brunella Posteraro
, Riccardo Torelli
, Mario Tumbarello
, David S. Perlin
, Giovanni Fadda
, Maurizio Sanguinetti

Public Health Research Institute, New York

Risultato della ricerca: Contributo in rivista › Articolo › peer review

55 Citazioni (Scopus)

Abstract

We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

Lingua originale	Inglese
pagine (da-a)	3031-3035
Numero di pagine	5
Rivista	Antimicrobial Agents and Chemotherapy
Volume	55
DOI	https://doi.org/10.1128/AAC.01569-10
Stato di pubblicazione	Pubblicato - 2011

Keywords

echinocandin

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title = "In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species",

abstract = "We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.",

keywords = "echinocandin, echinocandin",

author = "Barbara Fiori and Brunella Posteraro and Riccardo Torelli and Mario Tumbarello and Perlin, \{David S.\} and Giovanni Fadda and Maurizio Sanguinetti",

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doi = "10.1128/AAC.01569-10",

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T1 - In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

AU - Fiori, Barbara

AU - Posteraro, Brunella

AU - Torelli, Riccardo

AU - Tumbarello, Mario

AU - Perlin, David S.

AU - Fadda, Giovanni

AU - Sanguinetti, Maurizio

PY - 2011

Y1 - 2011

N2 - We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

AB - We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

KW - echinocandin

UR - http://hdl.handle.net/10807/1369

U2 - 10.1128/AAC.01569-10

DO - 10.1128/AAC.01569-10

M3 - Article

SN - 0066-4804

VL - 55

SP - 3031

EP - 3035

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

ER -

In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

Abstract

Keywords

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