In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

Brunella Posteraro; Maurizio Sanguinetti; Barbara Fiori Alfarano; Riccardo Torelli; Mario Tumbarello; Giovanni Fadda; David S. Perlin

doi:10.1128/AAC.01569-10

In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

Brunella Posteraro, Maurizio Sanguinetti, Barbara Fiori Alfarano, Riccardo Torelli, Mario Tumbarello, Giovanni Fadda, David S. Perlin

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

55 Citazioni (Scopus)

Abstract

We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

Lingua originale	English
pagine (da-a)	3031-3035
Numero di pagine	5
Rivista	Antimicrobial Agents and Chemotherapy
Volume	55
DOI	https://doi.org/10.1128/AAC.01569-10
Stato di pubblicazione	Pubblicato - 2011

Keywords

echinocandin

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10.1128/AAC.01569-10

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title = "In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species",

abstract = "We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.",

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In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species. / Posteraro, Brunella ; Sanguinetti, Maurizio; Fiori Alfarano, Barbara et al.

In: Antimicrobial Agents and Chemotherapy, Vol. 55, 2011, pag. 3031-3035.

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

TY - JOUR

T1 - In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

AU - Posteraro, Brunella

AU - Sanguinetti, Maurizio

AU - Fiori Alfarano, Barbara

AU - Torelli, Riccardo

AU - Tumbarello, Mario

AU - Fadda, Giovanni

AU - Perlin, David S.

PY - 2011

Y1 - 2011

N2 - We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

AB - We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

KW - echinocandin

UR - http://hdl.handle.net/10807/1369

U2 - 10.1128/AAC.01569-10

DO - 10.1128/AAC.01569-10

M3 - Article

VL - 55

SP - 3031

EP - 3035

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

ER -

In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

Abstract

Keywords

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