TY - JOUR
T1 - In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species
AU - Fiori, Barbara
AU - Posteraro, Brunella
AU - Torelli, Riccardo
AU - Tumbarello, Mario
AU - Perlin, David S.
AU - Fadda, Giovanni
AU - Sanguinetti, Maurizio
PY - 2011
Y1 - 2011
N2 - We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.
AB - We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC₉₀s (SMIC₉₀s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC₉₀s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC₉₀ values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.
KW - echinocandin
KW - echinocandin
UR - http://hdl.handle.net/10807/1369
U2 - 10.1128/AAC.01569-10
DO - 10.1128/AAC.01569-10
M3 - Article
SN - 0066-4804
VL - 55
SP - 3031
EP - 3035
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
ER -