In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species.

Brunella Posteraro; Mario Tumbarello; Giovanni Fadda; Maurizio Sanguinetti; Barbara Fiori Alfarano; Riccardo Torelli; David S Perlin

In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species.

Brunella Posteraro, Mario Tumbarello, Giovanni Fadda, Maurizio Sanguinetti, Barbara Fiori Alfarano, Riccardo Torelli, David S Perlin

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

55 Citazioni (Scopus)

Abstract

We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC(90)s (SMIC(90)s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC(90)s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC(90) values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

Lingua originale	English
pagine (da-a)	3031-3035
Numero di pagine	5
Rivista	Antimicrobial Agents and Chemotherapy
Volume	2011
Stato di pubblicazione	Pubblicato - 2011

Keywords

anidulafungin
aspergillus
biofilm
candida

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Posteraro, Brunella ; Tumbarello, Mario ; Fadda, Giovanni ; Sanguinetti, Maurizio ; Fiori Alfarano, Barbara ; Torelli, Riccardo ; Perlin, David S. / In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species. In: Antimicrobial Agents and Chemotherapy. 2011 ; Vol. 2011. pagg. 3031-3035.

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title = "In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species.",

abstract = "We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC(90)s (SMIC(90)s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC(90)s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC(90) values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.",

keywords = "anidulafungin, aspergillus, biofilm, candida, anidulafungin, aspergillus, biofilm, candida",

author = "Brunella Posteraro and Mario Tumbarello and Giovanni Fadda and Maurizio Sanguinetti and {Fiori Alfarano}, Barbara and Riccardo Torelli and Perlin, {David S}",

year = "2011",

language = "English",

volume = "2011",

pages = "3031--3035",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588",

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In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species. / Posteraro, Brunella; Tumbarello, Mario; Fadda, Giovanni; Sanguinetti, Maurizio; Fiori Alfarano, Barbara; Torelli, Riccardo; Perlin, David S.

In: Antimicrobial Agents and Chemotherapy, Vol. 2011, 2011, pag. 3031-3035.

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

TY - JOUR

T1 - In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species.

AU - Posteraro, Brunella

AU - Tumbarello, Mario

AU - Fadda, Giovanni

AU - Sanguinetti, Maurizio

AU - Fiori Alfarano, Barbara

AU - Torelli, Riccardo

AU - Perlin, David S

PY - 2011

Y1 - 2011

N2 - We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC(90)s (SMIC(90)s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC(90)s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC(90) values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

AB - We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC(90)s (SMIC(90)s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC(90)s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC(90) values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

KW - anidulafungin

KW - aspergillus

KW - biofilm

KW - candida

KW - anidulafungin

KW - aspergillus

KW - biofilm

KW - candida

UR - http://hdl.handle.net/10807/5846

M3 - Article

VL - 2011

SP - 3031

EP - 3035

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

ER -

In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species.

Abstract

Keywords

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