In search of a disease

Gustavo Savino, Andrea Campana, Md, Gianluigi Petrone, Gabriela Grimaldi, Ann P. Murchison

Risultato della ricerca: Contributo in rivistaArticolo in rivista

3 Citazioni (Scopus)


A 10-year-old child presented with right eyelid swelling and a palpable orbital mass. Diagnostic evaluation with the aid of excisional biopsy revealed a pseudoencapsulated mass associated with high levels of serum perinuclear antineutrophil cytoplasmic antibodies. Family history of rheumatic diseases, response to treatment with corticosteroids and immunosuppressant drugs, and clinical and histopathologic features suggested an orbital autoimmune response in which perinuclear antineutrophil cytoplasmic antibodies were detected, and a diagnosis of probable IgG4-related disease was made.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaSurvey of Ophthalmology
Stato di pubblicazionePubblicato - 2016


  • Intravenous steroids
  • Ophthalmology
  • Orbital IgG4-related disease
  • Pediatric orbital inflammatory disease
  • Perinuclear antineutrophil cytoplasmic antibodies (p-ANCA)
  • Subcutaneous methotrexate


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