Impulse control behaviours in patients with Parkinson's disease after subthalamic deep brain stimulation:De novo cases and 3-year follow-up

Alberto Albanese, Paolo Amami, Sylvie Piacentini, Luigi Michele Antonio Romito, Angelo Amato Franzini, P. Amami, I. Dekker, S. Piacentini, F. Ferré, L. M. Romito, A. Franzini, E. M.J. Foncke

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

51 Citazioni (Scopus)

Abstract

Objective To document the occurrence of impulse control behaviours (ICBs) in patients with Parkinson's disease after 3 years of continuous deep brain stimulation (DBS) of the subthalamic nucleus (STN). Methods Detailed neurological and ICB assessments were performed before STN DBS and up to 3 years after implant. Results 13 out of 56 patients (23.2%) had ICBs at baseline; they took higher doses of dopamine agonists (DAA). Three years after implant 11 had fully remitted with a 60.8% reduction of DAA medication; the remaining two, who had a similar medication reduction, had only compulsive eating, having recovered from hypersexuality. Six of the 43 patients without ICBs at baseline (14%) developed transient de novo ICBs after implant; none of them had ICBs at the 3-year observation. Conclusions ICBs were abolished in patients 3 years after STN DBS and DAA dosages were lowered. New ICBs may occur after implant and are transient in most cases. Compulsive eating may be speci fically related to STN stimulation.
Lingua originaleEnglish
pagine (da-a)562-564
Numero di pagine3
RivistaJOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY
Volume86
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • Behavioural Disorder
  • Deep Brain Stimulation
  • Disruptive, Impulse Control, and Conduct Disorders
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neurology (clinical)
  • Parkinson Disease
  • Parkinson's Disease
  • Prospective Studies
  • Psychiatry and Mental Health
  • Subthalamic Nucleus
  • Surgery

Fingerprint Entra nei temi di ricerca di 'Impulse control behaviours in patients with Parkinson's disease after subthalamic deep brain stimulation:De novo cases and 3-year follow-up'. Insieme formano una fingerprint unica.

Cita questo