Impact of IL-18 on inflammation

Domenico Tripodi, Franco Pandolfi, G Macauro, A Anogeianaki, M. L. Castellani, P Felaco, E Toniato, M. A. De Lutiis, M. Fulcheri, S. Tete, R. Galzio, V. Salini, A. Caraffa, P. Antinolfi, I. Frydas, G. Sabatino, Y. B. Shaik Dasthagirisaheb

Risultato della ricerca: Contributo in rivistaArticolo in rivista

6 Citazioni (Scopus)

Abstract

IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis since the T cells and macrophages that invade the synovial. These finding support a role for IL-18 in inflammation, allergy and immune diseases.
Lingua originaleEnglish
pagine (da-a)7-11
Numero di pagine5
RivistaJOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS
Stato di pubblicazionePubblicato - 2011

Keywords

  • Interleukin 18

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