Immunogenicity of anti-TNFα therapy in psoriasis: a clinical issue?

Clara De Simone, Paolo Amerio, Giuseppe Amoruso, Federico Bardazzi, Anna Campanati, Andrea Conti, Paolo Gisondi, Giulio Gualdi, Claudio Guarneri, Luca Leoni, Francesco Loconsole, Annamaria Mazzotta, Maria Letizia Musumeci, Stefano Piaserico, Concetta Potenza, Francesca Prestinari

Risultato della ricerca: Contributo in rivistaArticolo in rivista

56 Citazioni (Scopus)

Abstract

Immunogenicity of antitumor necrosis factor-alpha (TNFα) agents has been proven to play a significant role in the variability of clinical responses among patients with chronic inflammatory diseases. However, its clinical impact on the outcome of patients with psoriasis and psoriatic arthritis receiving anti-TNFα treatment is not yet fully clear. Despite the high rates of efficacy of anti-TNFα agents in psoriasis, a substantial proportion of patients remain who experience a primary or secondary failure or significant side effects, which are potentially ascribable to immunogenicity.
Lingua originaleEnglish
pagine (da-a)1673-1682
Numero di pagine10
RivistaExpert Opinion on Biological Therapy
Volume13
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • immunogenecity

Fingerprint Entra nei temi di ricerca di 'Immunogenicity of anti-TNFα therapy in psoriasis: a clinical issue?'. Insieme formano una fingerprint unica.

Cita questo