Immune thrombocytopenic purpura and percutaneous umbilical blood sampling: an open question

Sara De Carolis, Giuseppe Noia, Marco De Santis, C Trivellini, C Mastromarino, Maria Pia De Carolis, Sergio Ferrazzani, Alessandro Caruso

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)


We performed a retrospective study of 26 pregnancies with chronic immune thrombocytopenic purpura (ITP) or incidental ITP. Thirteen pregnancies were followed without the use of percutaneous umbilical blood sampling (PUBS) and 13 were followed sampling PUBS at 36-40 weeks of gestation. The overall prevalence of neonatal thrombocytopenia was 27%: 50% in chronic ITP, 12.5% in incidental ITP. Symptomatic thrombocytopenia occurred only in infants born to mothers with chronic ITP. Without the use of PUBS, 2 symptomatic thrombocytopenic fetuses were vaginally delivered and there was a high rate of cesarean sections in normal fetuses. Owing to PUBS, a decrease of the cesarean section rate in normal fetuses was observed, but one fetal bradycardia (due to the technique) was encountered. PUBS resulted helpful to indicate the best route of delivery and reducing unnecessary cesarean sections in women with chronic ITP, but in presence of incidental ITP the use of PUBS remains an open question.
Lingua originaleEnglish
pagine (da-a)154-160
Numero di pagine7
RivistaFetal Diagnosis and Therapy
Stato di pubblicazionePubblicato - 1993


  • Adult
  • Bradycardia
  • Chronic Disease
  • Cordocentesis
  • Delivery, Obstetric
  • Evaluation Studies as Topic
  • Female
  • Fetal Blood
  • Fetal Diseases
  • Humans
  • Infant, Newborn
  • Platelet Count
  • Pregnancy
  • Pregnancy Complications, Hematologic
  • Pregnancy Trimester, Third
  • Purpura, Thrombocytopenic, Idiopathic
  • Regression Analysis
  • Retrospective Studies
  • Thrombocytopenia


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