Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients

Massimiliano Fabbiani; Simona Di Giambenedetto; Michela Sali; Salvatore Farina; Paola Sansonetti; Enrica Tamburrini; Lorenzo Zileri Dal Verme; Giovanni Delogu; Andrea De Luca; David Kelvin; Roberto Cauda; Giovanni Fadda

doi:10.1016/j.vaccine.2011.02.020

Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients

Massimiliano Fabbiani
, Simona Di Giambenedetto
, Michela Sali^*
, Salvatore Farina
, Paola Sansonetti
, Enrica Tamburrini
, Lorenzo Zileri Dal Verme
, Giovanni Delogu
, Andrea De Luca
, David Kelvin
, Roberto Cauda
, Giovanni Fadda

^*Autore corrispondente per questo lavoro

University Health Network University of Toronto
Azienda Ospedaliera Universitaria Senese

Risultato della ricerca: Contributo in rivista › Articolo

27 Citazioni (Scopus)

Abstract

Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200. cells/Î¼L while individuals with CD4 <200. cells/Î¼L showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients. Â© 2011 Elsevier Ltd.

Lingua originale	Inglese
pagine (da-a)	2836-2839
Numero di pagine	4
Rivista	Vaccine
Volume	29
Numero di pubblicazione	16
DOI	https://doi.org/10.1016/j.vaccine.2011.02.020
Stato di pubblicazione	Pubblicato - 2011

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

SDG 3 Salute e benessere

All Science Journal Classification (ASJC) codes

Medicina Molecolare
Immunologia e Microbiologia Generali
Veterinaria Generale
Salute Pubblica, Salute Ambientale e Occupazionale
Malattie Infettive

Keywords

Adjuvants
Adult
Antibodies
CD4 Lymphocyte Count
Environmental and Occupational Health
Female
H1N1 Subtype
HIV
HIV Infections
Hemagglutinin Glycoproteins
Human
Humans
Immunogenicity
Immunologic
Immunology and Microbiology (all)
Infectious Diseases
Influenza
Influenza A (H1N1)
Influenza A Virus
Influenza Vaccines
Influenza Virus
Male
Middle Aged
Molecular Medicine
Polysorbates
Public Health
Squalene
Swine flu
Vaccination
Veterinary (all)
Viral

Accesso al documento

10.1016/j.vaccine.2011.02.020

Altri file e collegamenti

Cita questo

@article{557d6a56eadf412c91412a3f893e3a5d,

title = "Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients",

abstract = "Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200. cells/{\^I}¼L while individuals with CD4 <200. cells/{\^I}¼L showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients. {\^A}{\textcopyright} 2011 Elsevier Ltd.",

keywords = "Adjuvants, Adult, Antibodies, CD4 Lymphocyte Count, Environmental and Occupational Health, Female, H1N1 Subtype, HIV, HIV Infections, Hemagglutinin Glycoproteins, Human, Humans, Immunogenicity, Immunologic, Immunology and Microbiology (all), Infectious Diseases, Influenza, Influenza A (H1N1), Influenza A Virus, Influenza Vaccines, Influenza Virus, Male, Middle Aged, Molecular Medicine, Polysorbates, Public Health, Squalene, Swine flu, Vaccination, Veterinary (all), Viral, Adjuvants, Adult, Antibodies, CD4 Lymphocyte Count, Environmental and Occupational Health, Female, H1N1 Subtype, HIV, HIV Infections, Hemagglutinin Glycoproteins, Human, Humans, Immunogenicity, Immunologic, Immunology and Microbiology (all), Infectious Diseases, Influenza, Influenza A (H1N1), Influenza A Virus, Influenza Vaccines, Influenza Virus, Male, Middle Aged, Molecular Medicine, Polysorbates, Public Health, Squalene, Swine flu, Vaccination, Veterinary (all), Viral",

author = "Massimiliano Fabbiani and \{Di Giambenedetto\}, Simona and Michela Sali and Salvatore Farina and Paola Sansonetti and Enrica Tamburrini and Verme, \{Lorenzo Zileri Dal\} and Giovanni Delogu and \{De Luca\}, Andrea and David Kelvin and Roberto Cauda and Giovanni Fadda",

year = "2011",

doi = "10.1016/j.vaccine.2011.02.020",

language = "English",

volume = "29",

pages = "2836--2839",

journal = "Vaccine",

issn = "0264-410X",

publisher = "Elsevier Limited",

number = "16",

}

TY - JOUR

T1 - Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients

AU - Fabbiani, Massimiliano

AU - Di Giambenedetto, Simona

AU - Sali, Michela

AU - Farina, Salvatore

AU - Sansonetti, Paola

AU - Tamburrini, Enrica

AU - Verme, Lorenzo Zileri Dal

AU - Delogu, Giovanni

AU - De Luca, Andrea

AU - Kelvin, David

AU - Cauda, Roberto

AU - Fadda, Giovanni

PY - 2011

Y1 - 2011

N2 - Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200. cells/Î¼L while individuals with CD4 <200. cells/Î¼L showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients. Â© 2011 Elsevier Ltd.

AB - Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200. cells/Î¼L while individuals with CD4 <200. cells/Î¼L showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients. Â© 2011 Elsevier Ltd.

KW - Adjuvants

KW - Adult

KW - Antibodies

KW - CD4 Lymphocyte Count

KW - Environmental and Occupational Health

KW - Female

KW - H1N1 Subtype

KW - HIV

KW - HIV Infections

KW - Hemagglutinin Glycoproteins

KW - Human

KW - Humans

KW - Immunogenicity

KW - Immunologic

KW - Immunology and Microbiology (all)

KW - Infectious Diseases

KW - Influenza

KW - Influenza A (H1N1)

KW - Influenza A Virus

KW - Influenza Vaccines

KW - Influenza Virus

KW - Male

KW - Middle Aged

KW - Molecular Medicine

KW - Polysorbates

KW - Public Health

KW - Squalene

KW - Swine flu

KW - Vaccination

KW - Veterinary (all)

KW - Viral

KW - Adjuvants

KW - Adult

KW - Antibodies

KW - CD4 Lymphocyte Count

KW - Environmental and Occupational Health

KW - Female

KW - H1N1 Subtype

KW - HIV

KW - HIV Infections

KW - Hemagglutinin Glycoproteins

KW - Human

KW - Humans

KW - Immunogenicity

KW - Immunologic

KW - Immunology and Microbiology (all)

KW - Infectious Diseases

KW - Influenza

KW - Influenza A (H1N1)

KW - Influenza A Virus

KW - Influenza Vaccines

KW - Influenza Virus

KW - Male

KW - Middle Aged

KW - Molecular Medicine

KW - Polysorbates

KW - Public Health

KW - Squalene

KW - Swine flu

KW - Vaccination

KW - Veterinary (all)

KW - Viral

UR - https://publicatt.unicatt.it/handle/10807/104313

UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=79953219744&origin=inward

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79953219744&origin=inward

U2 - 10.1016/j.vaccine.2011.02.020

DO - 10.1016/j.vaccine.2011.02.020

M3 - Article

SN - 0264-410X

VL - 29

SP - 2836

EP - 2839

JO - Vaccine

JF - Vaccine

IS - 16

ER -

Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients

Abstract

OSS delle Nazioni Unite

All Science Journal Classification (ASJC) codes

Keywords

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo