Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients

Massimiliano Fabbiani, Simona Di Giambenedetto, Michela Sali, Salvatore Farina, Paola Sansonetti, Enrica Tamburrini, Lorenzo Zileri Dal Verme, Giovanni Delogu, Andrea De Luca, David Kelvin, Roberto Cauda, Giovanni Fadda

Risultato della ricerca: Contributo in rivistaArticolo in rivista

27 Citazioni (Scopus)

Abstract

Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200. cells/μL while individuals with CD4 <200. cells/μL showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients. © 2011 Elsevier Ltd.
Lingua originaleEnglish
pagine (da-a)2836-2839
Numero di pagine4
RivistaVaccine
Volume29
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Adjuvants, Immunologic
  • Adult
  • Antibodies, Viral
  • CD4 Lymphocyte Count
  • Female
  • HIV
  • HIV Infections
  • Hemagglutinin Glycoproteins, Influenza Virus
  • Humans
  • Immunogenicity
  • Immunology and Microbiology (all)
  • Infectious Diseases
  • Influenza A (H1N1)
  • Influenza A Virus, H1N1 Subtype
  • Influenza Vaccines
  • Influenza, Human
  • Male
  • Middle Aged
  • Molecular Medicine
  • Polysorbates
  • Public Health, Environmental and Occupational Health
  • Squalene
  • Swine flu
  • Vaccination
  • Veterinary (all)

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