IL-31 a Th2 cytokine involved in immunity and inflammation.

Ml Castellani, P. Felaco, R. J. Galzio, D. Tripodi, E. Toniato, M. A. De Lutiis, M. Fulcheri, A. Caraffa, P. Antinolfi, S. Tete, M. Felaco, F. Conti, Franco Pandolfi, T. C. Theoharides, Y. B. Shaiki Dathagirisaheb

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

11 Citazioni (Scopus)


Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.
Lingua originaleEnglish
pagine (da-a)709-713
Numero di pagine5
RivistaInternational Journal of Immunopathology and Pharmacology
Stato di pubblicazionePubblicato - 2010


  • IL-31


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