Abstract
Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.
Lingua originale | English |
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pagine (da-a) | 709-713 |
Numero di pagine | 5 |
Rivista | International Journal of Immunopathology and Pharmacology |
Stato di pubblicazione | Pubblicato - 2010 |
Keywords
- IL-31