IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia

P Bulian; D Rossi; F Forconi; G Del Poeta; F Bertoni; E Zucca; M Montillo; G Pozzato; G D'Arena; Dg Efremov; R Marasca; F Lauria; G Gaidano; V Gattei; Luca Laurenti

doi:10.1186/1479-5876-10-18

IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia

P Bulian^*
, D Rossi
, F Forconi
, G Del Poeta
, F Bertoni
, E Zucca
, M Montillo
, G Pozzato
, G D'Arena
, Dg Efremov
, R Marasca
, F Lauria
, G Gaidano
, V Gattei
, Luca Laurenti

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo

17 Citazioni (Scopus)

Abstract

Prognostic index for survival estimation by clinical-demographic variables were previously proposed in chronic lymphocytic leukemia (CLL) patients. Our objective was to test in a large retrospective cohort of CLL patients the prognostic power of biological and clinical-demographic variable in a comprehensive multivariate model. A new prognostic index was proposed.

Lingua originale	Inglese
pagine (da-a)	18-18
Numero di pagine	1
Rivista	Journal of Translational Medicine
Volume	10
Numero di pubblicazione	n/A
DOI	https://doi.org/10.1186/1479-5876-10-18
Stato di pubblicazione	Pubblicato - 2012

All Science Journal Classification (ASJC) codes

Biochimica, Genetica, Biologia Molecolare Generali

Keywords

80 and over
Adult
Aged
B-Cell
Biological
Chromosome Deletion
Chromosomes
Chronic
Cohort Studies
Female
Genes
Human
Humans
Immunoglobulin Heavy Chain
Kaplan-Meier Estimate
Leukemia
Lymphocytic
Male
Middle Aged
Models
Multivariate Analysis
Mutation
Nomograms
Pair 17
Proportional Hazards Models
Reproducibility of Results
Time Factors
Young Adult

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10.1186/1479-5876-10-18

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Bulian, P., Rossi, D., Forconi, F., Del Poeta, G., Bertoni, F., Zucca, E., Montillo, M., Pozzato, G., D'Arena, G., Efremov, D., Marasca, R., Lauria, F., Gaidano, G., Gattei, V., & Laurenti, L. (2012). IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia. Journal of Translational Medicine, 10(n/A), 18-18. https://doi.org/10.1186/1479-5876-10-18

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title = "IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia",

abstract = "Prognostic index for survival estimation by clinical-demographic variables were previously proposed in chronic lymphocytic leukemia (CLL) patients. Our objective was to test in a large retrospective cohort of CLL patients the prognostic power of biological and clinical-demographic variable in a comprehensive multivariate model. A new prognostic index was proposed.",

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author = "P Bulian and D Rossi and F Forconi and \{Del Poeta\}, G and F Bertoni and E Zucca and M Montillo and G Pozzato and G D'Arena and Dg Efremov and R Marasca and F Lauria and G Gaidano and V Gattei and Luca Laurenti",

year = "2012",

doi = "10.1186/1479-5876-10-18",

language = "English",

volume = "10",

pages = "18--18",

journal = "Journal of Translational Medicine",

issn = "1479-5876",

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Bulian, P, Rossi, D, Forconi, F, Del Poeta, G, Bertoni, F, Zucca, E, Montillo, M, Pozzato, G, D'Arena, G, Efremov, D, Marasca, R, Lauria, F, Gaidano, G, Gattei, V & Laurenti, L 2012, 'IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia', Journal of Translational Medicine, vol. 10, n. n/A, pagg. 18-18. https://doi.org/10.1186/1479-5876-10-18

IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia. / Bulian, P; Rossi, D; Forconi, F et al.
In: Journal of Translational Medicine, Vol. 10, N. n/A, 2012, pag. 18-18.

Risultato della ricerca: Contributo in rivista › Articolo

TY - JOUR

T1 - IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia

AU - Bulian, P

AU - Rossi, D

AU - Forconi, F

AU - Del Poeta, G

AU - Bertoni, F

AU - Zucca, E

AU - Montillo, M

AU - Pozzato, G

AU - D'Arena, G

AU - Efremov, Dg

AU - Marasca, R

AU - Lauria, F

AU - Gaidano, G

AU - Gattei, V

AU - Laurenti, Luca

PY - 2012

Y1 - 2012

N2 - Prognostic index for survival estimation by clinical-demographic variables were previously proposed in chronic lymphocytic leukemia (CLL) patients. Our objective was to test in a large retrospective cohort of CLL patients the prognostic power of biological and clinical-demographic variable in a comprehensive multivariate model. A new prognostic index was proposed.

AB - Prognostic index for survival estimation by clinical-demographic variables were previously proposed in chronic lymphocytic leukemia (CLL) patients. Our objective was to test in a large retrospective cohort of CLL patients the prognostic power of biological and clinical-demographic variable in a comprehensive multivariate model. A new prognostic index was proposed.

KW - 80 and over

KW - Adult

KW - Aged

KW - B-Cell

KW - Biological

KW - Chromosome Deletion

KW - Chromosomes

KW - Chronic

KW - Cohort Studies

KW - Female

KW - Genes

KW - Human

KW - Humans

KW - Immunoglobulin Heavy Chain

KW - Kaplan-Meier Estimate

KW - Leukemia

KW - Lymphocytic

KW - Male

KW - Middle Aged

KW - Models

KW - Multivariate Analysis

KW - Mutation

KW - Nomograms

KW - Pair 17

KW - Proportional Hazards Models

KW - Reproducibility of Results

KW - Time Factors

KW - Young Adult

KW - 80 and over

KW - Adult

KW - Aged

KW - B-Cell

KW - Biological

KW - Chromosome Deletion

KW - Chromosomes

KW - Chronic

KW - Cohort Studies

KW - Female

KW - Genes

KW - Human

KW - Humans

KW - Immunoglobulin Heavy Chain

KW - Kaplan-Meier Estimate

KW - Leukemia

KW - Lymphocytic

KW - Male

KW - Middle Aged

KW - Models

KW - Multivariate Analysis

KW - Mutation

KW - Nomograms

KW - Pair 17

KW - Proportional Hazards Models

KW - Reproducibility of Results

KW - Time Factors

KW - Young Adult

UR - https://publicatt.unicatt.it/handle/10807/40269

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U2 - 10.1186/1479-5876-10-18

DO - 10.1186/1479-5876-10-18

M3 - Article

SN - 1479-5876

VL - 10

SP - 18

EP - 18

JO - Journal of Translational Medicine

JF - Journal of Translational Medicine

IS - n/A

ER -

IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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