TY - JOUR
T1 - -Idiopathic chronic urticaria and celiac disease
AU - Gabrielli, Maurizio
AU - Candelli, Marcello
AU - Cremonini, Filippo
AU - Ojetti, Veronica
AU - Santarelli, Luca
AU - Nista, Enrico Celestino
AU - Nucera, Eleonora
AU - Schiavino, Domenico
AU - Patriarca, Giampiero
AU - Gasbarrini, Giovanni Battista
AU - Pola, Paolo
AU - Gasbarrini, Antonio
PY - 2005
Y1 - 2005
N2 - Abstract
Idiopathic chronic urticaria (ICU) is a chronic relapsing cutaneous disease. Some case reports or studies on small series of celiac disease (CD) patients have suggested a possible association between CD and ICU. The aim of this study was to assess the prevalence of CD in a population of adults ICU patients with respect to healthy controls. We consecutively enrolled 80 patients affected by ICU and 264 blood donors as the control population without a history of ICU. Serum anti-transglutaminase IgG and anti-endomysium IgA antibodies were evaluated in all subjects. In the case of positivity to serology, diagnosis was confirmed by duodenal biopsy. One of 80 (1.25%) ICU patients were positive to both anti-transglutaminase and anti-endomysium antibodies. Duodenal biopsy showed partial villous atrophy. One control of 264 (0.38%) had CD. No statistical difference was found in the prevalence of CD between the two groups. ICU patients do not seem to bear a greater risk for CD compared to the general population.
AB - Abstract
Idiopathic chronic urticaria (ICU) is a chronic relapsing cutaneous disease. Some case reports or studies on small series of celiac disease (CD) patients have suggested a possible association between CD and ICU. The aim of this study was to assess the prevalence of CD in a population of adults ICU patients with respect to healthy controls. We consecutively enrolled 80 patients affected by ICU and 264 blood donors as the control population without a history of ICU. Serum anti-transglutaminase IgG and anti-endomysium IgA antibodies were evaluated in all subjects. In the case of positivity to serology, diagnosis was confirmed by duodenal biopsy. One of 80 (1.25%) ICU patients were positive to both anti-transglutaminase and anti-endomysium antibodies. Duodenal biopsy showed partial villous atrophy. One control of 264 (0.38%) had CD. No statistical difference was found in the prevalence of CD between the two groups. ICU patients do not seem to bear a greater risk for CD compared to the general population.
KW - urticaria and celiac disease
KW - urticaria and celiac disease
UR - http://hdl.handle.net/10807/21088
M3 - Article
SN - 0163-2116
SP - 1702
EP - 1704
JO - Digestive Diseases and Sciences
JF - Digestive Diseases and Sciences
ER -