Identifying and addressing unmet clinical needs in Ph-neg classical myeloproliferative neoplasms: a consensus-based SIE, SIES, GITMO position paper

Valerio De Stefano, Giovanni Barosi, Alessandro M. Vannucchi, Fabrizio Pane, Francesco Passamonti, Alessandro Rambaldi, Giuseppe Saglio, Tiziano Barbui, Sante Tura

Risultato della ricerca: Contributo in rivistaArticolo in rivista

23 Citazioni (Scopus)

Abstract

This article presents the results of group discussion among experts from SIE, SIES and GITMO societies aimed at highlighting unmet challenges in the management of Ph-neg myeloproliferative neoplasms (MPNs). The issues analyzed were: diagnosis of prefibrotic myelofibrosis; diagnosis of Ph-neg MPNs in the setting of splanchnic vein thrombosis (SVT); management of low-risk PV and low-risk ET patients with JAK2V617F mutation; molecular biomarkers in the prognostic evaluation of myelofibrosis (MF); ruxolitinib therapy in low-risk MF; therapy in patients with SVT-associated Ph-neg MPN; indications of splenectomy in MF. For each of these issues, proposals for advancement in clinical research were addressed.
Lingua originaleEnglish
pagine (da-a)155-160
Numero di pagine6
RivistaLeukemia Research
Volume38
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • Consensus
  • Essential thrombocythemia
  • Expert Testimony
  • Myelofibrosis
  • Myeloproliferative Disorders
  • Myeloproliferative neoplasm
  • Unmet clinical need
  • polycythemia vera

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