Identification of Molds by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry

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72 Citazioni (Scopus)

Abstract

Although to a lesser extent than diagnostic bacteriology, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has recently revolutionized the diagnostic mycology workflow. With regard to filamentous fungi (or molds), the precise recognition of pathogenic species is important for rapid diagnosis and appropriate treatment, especially for invasive diseases. This review summarizes the current experience with MALDI-TOF MS-based identification of common and uncommon mold species of Aspergillus, Fusarium, Mucorales, dimorphic fungi, and dermatophytes. This experience clearly shows that MALDI-TOF MS holds promise as a fast and accurate identification tool, particularly with common species or typical strains of filamentous fungi.
Lingua originaleEnglish
pagine (da-a)369-379
Numero di pagine11
RivistaJournal of Clinical Microbiology
Volume55
DOI
Stato di pubblicazionePubblicato - 2017

Keywords

  • MALDI-TOF MS
  • filamentous fungi

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