Hypervascularity Predicts Complete Pathologic Response to Chemotherapy and Late Outcomes in Breast Cancer

Paolo Belli, Gianluca Franceschini, Enida Bufi, Marialuisa Di Matteo, Michela Giuliani, Mariavalentina Tumino, Pierluigi Rinaldi, Luigia Nardone, Antonino Mule', Lorenzo Bonomo

Risultato della ricerca: Contributo in rivistaArticolo in rivista

4 Citazioni (Scopus)

Abstract

Micro-Abstract Asymmetric increase in breast vascularity (AIBV) is an emerging marker in magnetic resonance imaging-based evaluation of breast cancer. We analyze herein the largest series so far aimed at elucidating the potential role of AIBV in predicting the early and late outcomes of locally advanced breast cancer. We observed that, despite more aggressive pathologic profile of tumors associated with AIBV, they also present greater sensitivity to neoadjuvant chemotherapy. Nonetheless, the persistence of AIBV after neoadjuvant chemotherapy is associated with worse late prognosis and might be used to tailor additional treatments.
Lingua originaleEnglish
pagine (da-a)e193-e201
Numero di pagine9
RivistaClinical Breast Cancer
Volume16
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • Breast tumor
  • Cancer Research
  • Increased vascularization
  • Magnetic Resonance Imaging
  • Neoadjuvant chemotherapy
  • Oncology
  • Prognosis

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