Abstract
Patients with inflammatory bowel disease (IBD) have an increased risk of thrombotic complications. Moreover, a hypercoagulable state has been hypothesized as a contributing factor in the pathogenesis of IBD. Recently, a growing amount of interest has focused on mild-to-moderate hyperhomocysteinemia as a risk factor for thromboembolic disease. We aimed to evaluate the prevalence of hyperhomocysteinemia in patients with IBD and to investigate the contribution of genetic defects in the enzymes involved in homocysteine (Hcy) metabolism and vitamin status in determining increased levels of plasma total Hcy (tHcy).
Lingua originale | English |
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pagine (da-a) | 2677-2682 |
Numero di pagine | 6 |
Rivista | THE AMERICAN JOURNAL OF GASTROENTEROLOGY |
Volume | 96 |
DOI | |
Stato di pubblicazione | Pubblicato - 2001 |
Keywords
- Homocysteine
- Hyperhomocysteinemia
- Inflammatory Bowel Diseases
- Polymorphism, Genetic
- Prevalence