Hydrocephalus and Chiari type I malformation

Concezio Di Rocco, Paolo Frassanito, Luca Massimi, Simone Peraio

Risultato della ricerca: Contributo in rivistaArticolo in rivista

54 Citazioni (Scopus)

Abstract

INTODUCTION: Hydrocephalus has been related to Chiari type I malformation (CIM) for a long time. The pathogenesis of this association is complex and still debated. DISCUSSION: A supratentorial hypertensive hydrocephalus may cause CIM, exerting pressure from above. Another pathogenetic hypothesis is based on the clinical and radiological data from patients affected by complex craniosynostosis, in which this association is more commonly observed as the consequence of a "cephalo-cranial disproportion" ultimately leading to a secondary hydrocephalus. In some cases, the concomitant presence of a stenosis of the jugular foramina would determine a condition of upward venous hypertension, resulting in the development of CIM and an associated hydrocephalus due to cerebellar parenchyma turgor. CONCLUSIONS: The radiological association of ventricular enlargement and hindbrain herniation would be the result of heterogeneous pathogenetic mechanisms which would then require specific therapeutic approaches. In this context, the endoscopic third ventricle-cisternostomy is gaining an increasing interest because of its more physiologic correction of the altered CSF dynamics and its minor interference on the developmental processes responsible for the association of hydrocephalus and CIM.
Lingua originaleEnglish
pagine (da-a)1653-1664
Numero di pagine12
RivistaCHILD'S NERVOUS SYSTEM
Volume27
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Arnold-Chiari Malformation
  • Cranial Fossa, Posterior
  • Humans
  • Hydrocephalus
  • Magnetic Resonance Imaging

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