Abstract
In patients with chronic congenital haemolytic disorders, human Parvovirus B19 (HPV B19) is frequently involved in pure red-cell aplastic crises. Furthermore, it may inhibit three-lineage haematopoiesis in the bone marrow, causing severe pancytopenia. In such patients, Epstein Barr virus (EBV) infection also seems to share the same mechanism as HPV B19 in inducing bone marrow aplasia, but at present the clinical effect of an infection sustained by both viruses is unknown.
| Lingua originale | Inglese |
|---|---|
| pagine (da-a) | 265-269 |
| Numero di pagine | 5 |
| Rivista | European Review for Medical and Pharmacological Sciences |
| Volume | 16 |
| Numero di pubblicazione | 2 |
| Stato di pubblicazione | Pubblicato - 2012 |
All Science Journal Classification (ASJC) codes
- Farmacologia (medica)
Keywords
- Anemia
- Aplastic
- Child
- Coinfection
- Epstein-Barr Virus Infections
- Hereditary
- Herpesvirus 4
- Human
- Humans
- Male
- Parvoviridae Infections
- Parvovirus B19
- Spherocytosis