TY - JOUR
T1 - Human parvovirus B 19 and Epstein-Barr virus co-infection in a child with hereditary spherocytosis
AU - Cefalo, Maria Giuseppina
AU - Arlotta, A.
AU - Maurizi, Palma
AU - Russo, Ida
AU - Sani, Ilaria
AU - Battista, A.
AU - Mastrangelo, Stefano
AU - Ruggiero, Antonio
AU - Riccardi, Riccardo
PY - 2012
Y1 - 2012
N2 - In patients with chronic congenital haemolytic disorders, human Parvovirus B19 (HPV B19) is frequently involved in pure red-cell aplastic crises. Furthermore, it may inhibit three-lineage haematopoiesis in the bone marrow, causing severe pancytopenia. In such patients, Epstein Barr virus (EBV) infection also seems to share the same mechanism as HPV B19 in inducing bone marrow aplasia, but at present the clinical effect of an infection sustained by both viruses is unknown.
AB - In patients with chronic congenital haemolytic disorders, human Parvovirus B19 (HPV B19) is frequently involved in pure red-cell aplastic crises. Furthermore, it may inhibit three-lineage haematopoiesis in the bone marrow, causing severe pancytopenia. In such patients, Epstein Barr virus (EBV) infection also seems to share the same mechanism as HPV B19 in inducing bone marrow aplasia, but at present the clinical effect of an infection sustained by both viruses is unknown.
KW - Anemia, Aplastic
KW - Child
KW - Coinfection
KW - Epstein-Barr Virus Infections
KW - Herpesvirus 4, Human
KW - Humans
KW - Male
KW - Parvoviridae Infections
KW - Parvovirus B19, Human
KW - Spherocytosis, Hereditary
KW - Anemia, Aplastic
KW - Child
KW - Coinfection
KW - Epstein-Barr Virus Infections
KW - Herpesvirus 4, Human
KW - Humans
KW - Male
KW - Parvoviridae Infections
KW - Parvovirus B19, Human
KW - Spherocytosis, Hereditary
UR - http://hdl.handle.net/10807/23231
M3 - Article
SN - 1128-3602
VL - 16
SP - 265
EP - 269
JO - European Review for Medical and Pharmacological Sciences
JF - European Review for Medical and Pharmacological Sciences
ER -