Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study

Michela Sali, Gian Franco Zannoni, Rosaria Santangelo, Giovanni Almadori, Jacopo Galli, Giovanni Delogu, Maurizio Sanguinetti, Guido Rindi, Vincenzo Valentini, Gaetano Paludetti, Francesco Bussu, Roberto Gallus, Gianluigi Petrone, Rosa Autorino, Nicola Dinapoli, Valerio Gaetano Vellone, Cristina Graziani, Francesco Micciche', Massimo Tommasino

Risultato della ricerca: Contributo in rivistaArticolo in rivista

31 Citazioni (Scopus)

Abstract

Human papillomavirus (HPV) 16 infection is associated with oropharyngeal carcinogenesis and is likely the cause of the reported increase in disease incidence. We evaluated the prevalence of HPV infection and the reliability of different diagnostic tools using primary tumor samples from a cohort of 50 patients.
Lingua originaleEnglish
pagine (da-a)1115-1120
Numero di pagine6
RivistaInternational Journal of Radiation Oncology Biology Physics
Volume89
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • Aged
  • Carcinoma, Squamous Cell
  • DNA, Viral
  • Female
  • Human papillomavirus 16
  • Humans
  • Male
  • Middle Aged
  • Oropharyngeal Neoplasms
  • Papillomavirus Infections
  • Paraffin Embedding
  • Pilot Projects
  • Prevalence
  • Prognosis
  • RNA, Viral
  • Reproducibility of Results

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