Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study

Francesco Bussu; Michela Sali; Roberto Gallus; Gianluigi Petrone; Gian Franco Zannoni; Rosa Autorino; Nicola Dinapoli; Rosaria Santangelo; Valerio Gaetano Vellone; Cristina Graziani; Francesco Micciche'; Giovanni Almadori; Jacopo Galli; Giovanni Delogu; Maurizio Sanguinetti; Guido Rindi; Massimo Tommasino; Vincenzo Valentini; Gaetano Paludetti

doi:10.1016/j.ijrobp.2014.04.044

Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study

Francesco Bussu, Michela Sali, Roberto Gallus, Gianluigi Petrone, Gian Franco Zannoni, Rosa Autorino, Nicola Dinapoli, Rosaria Santangelo, Valerio Gaetano Vellone, Cristina Graziani, Francesco Micciche', Giovanni Almadori, Jacopo Galli, Giovanni Delogu, Maurizio Sanguinetti, Guido Rindi, Massimo Tommasino, Vincenzo Valentini, Gaetano Paludetti

Risultato della ricerca: Contributo in rivista › Articolo in rivista

31 Citazioni (Scopus)

Abstract

Human papillomavirus (HPV) 16 infection is associated with oropharyngeal carcinogenesis and is likely the cause of the reported increase in disease incidence. We evaluated the prevalence of HPV infection and the reliability of different diagnostic tools using primary tumor samples from a cohort of 50 patients.

Lingua originale	English
pagine (da-a)	1115-1120
Numero di pagine	6
Rivista	International Journal of Radiation Oncology Biology Physics
Volume	89
DOI	https://doi.org/10.1016/j.ijrobp.2014.04.044
Stato di pubblicazione	Pubblicato - 2014

Keywords

Aged
Carcinoma, Squamous Cell
DNA, Viral
Female
Human papillomavirus 16
Humans
Male
Middle Aged
Oropharyngeal Neoplasms
Papillomavirus Infections
Paraffin Embedding
Pilot Projects
Prevalence
Prognosis
RNA, Viral
Reproducibility of Results

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10.1016/j.ijrobp.2014.04.044

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Bussu, F., Sali, M., Gallus, R., Petrone, G., Zannoni, G. F., Autorino, R., Dinapoli, N., Santangelo, R., Vellone, V. G., Graziani, C., Micciche', F., Almadori, G., Galli, J., Delogu, G., Sanguinetti, M., Rindi, G., Tommasino, M., Valentini, V., & Paludetti, G. (2014). Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study. International Journal of Radiation Oncology Biology Physics, 89, 1115-1120. https://doi.org/10.1016/j.ijrobp.2014.04.044

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title = "Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study",

abstract = "Human papillomavirus (HPV) 16 infection is associated with oropharyngeal carcinogenesis and is likely the cause of the reported increase in disease incidence. We evaluated the prevalence of HPV infection and the reliability of different diagnostic tools using primary tumor samples from a cohort of 50 patients.",

keywords = "Aged, Carcinoma, Squamous Cell, DNA, Viral, Female, Human papillomavirus 16, Humans, Male, Middle Aged, Oropharyngeal Neoplasms, Papillomavirus Infections, Paraffin Embedding, Pilot Projects, Prevalence, Prognosis, RNA, Viral, Reproducibility of Results, Aged, Carcinoma, Squamous Cell, DNA, Viral, Female, Human papillomavirus 16, Humans, Male, Middle Aged, Oropharyngeal Neoplasms, Papillomavirus Infections, Paraffin Embedding, Pilot Projects, Prevalence, Prognosis, RNA, Viral, Reproducibility of Results",

author = "Francesco Bussu and Michela Sali and Roberto Gallus and Gianluigi Petrone and Zannoni, {Gian Franco} and Rosa Autorino and Nicola Dinapoli and Rosaria Santangelo and Vellone, {Valerio Gaetano} and Cristina Graziani and Francesco Micciche' and Giovanni Almadori and Jacopo Galli and Giovanni Delogu and Maurizio Sanguinetti and Guido Rindi and Massimo Tommasino and Vincenzo Valentini and Gaetano Paludetti",

year = "2014",

doi = "10.1016/j.ijrobp.2014.04.044",

language = "English",

volume = "89",

pages = "1115--1120",

journal = "International Journal of Radiation Oncology Biology Physics",

issn = "0360-3016",

publisher = "Elsevier Inc.",

}

Bussu, F, Sali, M, Gallus, R, Petrone, G, Zannoni, GF, Autorino, R, Dinapoli, N, Santangelo, R, Vellone, VG, Graziani, C, Micciche', F, Almadori, G , Galli, J , Delogu, G , Sanguinetti, M , Rindi, G, Tommasino, M, Valentini, V & Paludetti, G 2014, 'Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study', International Journal of Radiation Oncology Biology Physics, vol. 89, pagg. 1115-1120. https://doi.org/10.1016/j.ijrobp.2014.04.044

Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study. / Bussu, Francesco; Sali, Michela; Gallus, Roberto et al.
In: International Journal of Radiation Oncology Biology Physics, Vol. 89, 2014, pag. 1115-1120.

Risultato della ricerca: Contributo in rivista › Articolo in rivista

TY - JOUR

T1 - Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study

AU - Bussu, Francesco

AU - Sali, Michela

AU - Gallus, Roberto

AU - Petrone, Gianluigi

AU - Zannoni, Gian Franco

AU - Autorino, Rosa

AU - Dinapoli, Nicola

AU - Santangelo, Rosaria

AU - Vellone, Valerio Gaetano

AU - Graziani, Cristina

AU - Micciche', Francesco

AU - Almadori, Giovanni

AU - Galli, Jacopo

AU - Delogu, Giovanni

AU - Sanguinetti, Maurizio

AU - Rindi, Guido

AU - Tommasino, Massimo

AU - Valentini, Vincenzo

AU - Paludetti, Gaetano

PY - 2014

Y1 - 2014

N2 - Human papillomavirus (HPV) 16 infection is associated with oropharyngeal carcinogenesis and is likely the cause of the reported increase in disease incidence. We evaluated the prevalence of HPV infection and the reliability of different diagnostic tools using primary tumor samples from a cohort of 50 patients.

AB - Human papillomavirus (HPV) 16 infection is associated with oropharyngeal carcinogenesis and is likely the cause of the reported increase in disease incidence. We evaluated the prevalence of HPV infection and the reliability of different diagnostic tools using primary tumor samples from a cohort of 50 patients.

KW - Aged

KW - Carcinoma, Squamous Cell

KW - DNA, Viral

KW - Female

KW - Human papillomavirus 16

KW - Humans

KW - Male

KW - Middle Aged

KW - Oropharyngeal Neoplasms

KW - Papillomavirus Infections

KW - Paraffin Embedding

KW - Pilot Projects

KW - Prevalence

KW - Prognosis

KW - RNA, Viral

KW - Reproducibility of Results

KW - Aged

KW - Carcinoma, Squamous Cell

KW - DNA, Viral

KW - Female

KW - Human papillomavirus 16

KW - Humans

KW - Male

KW - Middle Aged

KW - Oropharyngeal Neoplasms

KW - Papillomavirus Infections

KW - Paraffin Embedding

KW - Pilot Projects

KW - Prevalence

KW - Prognosis

KW - RNA, Viral

KW - Reproducibility of Results

UR - http://hdl.handle.net/10807/60259

U2 - 10.1016/j.ijrobp.2014.04.044

DO - 10.1016/j.ijrobp.2014.04.044

M3 - Article

SN - 0360-3016

VL - 89

SP - 1115

EP - 1120

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

ER -

Bussu F, Sali M, Gallus R, Petrone G, Zannoni GF, Autorino R et al. Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study. International Journal of Radiation Oncology Biology Physics. 2014;89:1115-1120. doi: 10.1016/j.ijrobp.2014.04.044

Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators--a pilot study

Abstract

Keywords

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