Human monoclonal antibody fragment specific for glycoprotein G in Herpes simplex type 2 with applications for serotype-specific diagnosis

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

Abstract

A combinatorial library was used to select a human monoclonal antibody fragment (Fab) with high affinity for G glycoprotein in herpes simplex virus type 2 (HSV-2). Tests with 112 clinical specimens demonstrated successful discrimination between HSV-2 and HSV-1, showing the potential of Fab as a low-cost tool for HSV subtyping in clinical diagnosis.
Lingua originaleEnglish
pagine (da-a)1250-1253
Numero di pagine4
RivistaJournal of Clinical Microbiology
Stato di pubblicazionePubblicato - 2004

Keywords

  • Glycoprotein G
  • Human recombinant antibodies
  • herpes simplex

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