How to Assess Drug Resistance in Cancer Stem Cells

Maria Laura De Angelis; Ruggero De Maria Marchiano; Marta Baiocchi

doi:10.1007/978-1-4939-7401-6_10

How to Assess Drug Resistance in Cancer Stem Cells

Maria Laura De Angelis, Ruggero De Maria Marchiano, Marta Baiocchi

Istituto Superiore di Sanita

Risultato della ricerca: Contributo in libro › Chapter

4 Citazioni (Scopus)

Abstract

Banks of genetically characterized cancer stem cells (CSCs) isolated from individual patients and grown as spheroids offer an invaluable approach to identify genetic determinants of drug resistance versus sensitivity, and to study new stem cell-directed therapies. Here, we describe our standardized procedure for in vitro drug screening on colorectal CSCs, taking irinotecan as an example.

Lingua originale	English
Titolo della pubblicazione ospite	Cancer Stem Cells: Methods and Protocols
Pagine	N/A
Numero di pagine	9
DOI	https://doi.org/10.1007/978-1-4939-7401-6_10
Stato di pubblicazione	Pubblicato - 2017

Serie di pubblicazioni

Nome	METHODS IN MOLECULAR BIOLOGY

Keywords

cancer stem cells
drug screening

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10.1007/978-1-4939-7401-6_10

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title = "How to Assess Drug Resistance in Cancer Stem Cells",

abstract = "Banks of genetically characterized cancer stem cells (CSCs) isolated from individual patients and grown as spheroids offer an invaluable approach to identify genetic determinants of drug resistance versus sensitivity, and to study new stem cell-directed therapies. Here, we describe our standardized procedure for in vitro drug screening on colorectal CSCs, taking irinotecan as an example.",

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author = "{De Angelis}, {Maria Laura} and {De Maria Marchiano}, Ruggero and Marta Baiocchi",

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T1 - How to Assess Drug Resistance in Cancer Stem Cells

AU - De Angelis, Maria Laura

AU - De Maria Marchiano, Ruggero

AU - Baiocchi, Marta

PY - 2017

Y1 - 2017

N2 - Banks of genetically characterized cancer stem cells (CSCs) isolated from individual patients and grown as spheroids offer an invaluable approach to identify genetic determinants of drug resistance versus sensitivity, and to study new stem cell-directed therapies. Here, we describe our standardized procedure for in vitro drug screening on colorectal CSCs, taking irinotecan as an example.

AB - Banks of genetically characterized cancer stem cells (CSCs) isolated from individual patients and grown as spheroids offer an invaluable approach to identify genetic determinants of drug resistance versus sensitivity, and to study new stem cell-directed therapies. Here, we describe our standardized procedure for in vitro drug screening on colorectal CSCs, taking irinotecan as an example.

KW - cancer stem cells

KW - drug screening

KW - cancer stem cells

KW - drug screening

UR - http://hdl.handle.net/10807/111255

U2 - 10.1007/978-1-4939-7401-6_10

DO - 10.1007/978-1-4939-7401-6_10

M3 - Chapter

SN - 1588299384

T3 - METHODS IN MOLECULAR BIOLOGY

SP - N/A

BT - Cancer Stem Cells: Methods and Protocols

ER -

How to Assess Drug Resistance in Cancer Stem Cells

Abstract

Serie di pubblicazioni

Keywords

OSS delle Nazioni Unite

Accesso al documento

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