TY - JOUR
T1 - How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion
AU - Rausei, Stefano
AU - Galli, Federica
AU - Lianos, Georgios
AU - Rosa, Fausto
AU - Cossu, Andrea
AU - Biondi, Alberto
AU - Martignoni, Francesco
AU - Cananzi, Ferdinando Carlo Maria
AU - Fumagalli, Uberto
AU - Alfieri, Sergio
AU - Persiani, Roberto
AU - Quagliuolo, Vittorio
AU - D'Ugo, Domenico
AU - Rosati, Riccardo
PY - 2020
Y1 - 2020
N2 - AimTo compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer.Patients and MethodsWe analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes.ResultsOf 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%; p < 0.001) and between patients with total examined lymph nodes >= 28 and < 28 (74.5% versus 62.3%; p = 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter.ConclusionWe should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.
AB - AimTo compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer.Patients and MethodsWe analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes.ResultsOf 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%; p < 0.001) and between patients with total examined lymph nodes >= 28 and < 28 (74.5% versus 62.3%; p = 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter.ConclusionWe should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.
KW - Cancer-related survival
KW - Number of removed lymph nodes
KW - Lymphadenectomy
KW - Locally advanced gastric cancer
KW - Cancer-related survival
KW - Number of removed lymph nodes
KW - Lymphadenectomy
KW - Locally advanced gastric cancer
UR - http://hdl.handle.net/10807/297263
U2 - 10.1007/s12029-019-00321-x
DO - 10.1007/s12029-019-00321-x
M3 - Article
SN - 1941-6628
VL - 51
SP - 887
EP - 892
JO - Journal of Gastrointestinal Cancer
JF - Journal of Gastrointestinal Cancer
ER -
