TY - JOUR
T1 - How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion
AU - Rausei, S.
AU - Galli, F.
AU - Lianos, G.
AU - Rosa, Fausto
AU - Cossu, A.
AU - Biondi, Alberto
AU - Martignoni, F.
AU - Cananzi, F. C. M.
AU - Fumagalli, U.
AU - Alfieri, Sergio
AU - Persiani, Roberto
AU - Quagliuolo, V.
AU - D'Ugo, Domenico
AU - Rosati, R.
PY - 2019
Y1 - 2019
N2 - Aim: To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer. Patients and Methods: We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes. Results: Of 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%; p < 0.001) and between patients with total examined lymph nodes ≥ 28 and < 28 (74.5% versus 62.3%; p = 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter. Conclusion: We should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.
AB - Aim: To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer. Patients and Methods: We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes. Results: Of 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%; p < 0.001) and between patients with total examined lymph nodes ≥ 28 and < 28 (74.5% versus 62.3%; p = 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter. Conclusion: We should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.
KW - Cancer-related survival
KW - Locally advanced gastric cancer
KW - Lymphadenectomy
KW - Number of removed lymph nodes
KW - Cancer-related survival
KW - Locally advanced gastric cancer
KW - Lymphadenectomy
KW - Number of removed lymph nodes
UR - https://publicatt.unicatt.it/handle/10807/147350
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85074779091&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85074779091&origin=inward
U2 - 10.1007/s12029-019-00321-x
DO - 10.1007/s12029-019-00321-x
M3 - Article
SN - 1941-6628
SP - N/A-N/A
JO - Journal of Gastrointestinal Cancer
JF - Journal of Gastrointestinal Cancer
IS - NA
ER -
