How metformin acts in PCOS pregnant women: insights into insulin secretion and peripheral action at each trimester of gestation

Daniela Romualdi; Simona De Cicco; D Gagliano; M Busacca; G Campagna; Antonio Lanzone; Maurizio Guido

doi:10.2337/dc12-2071

How metformin acts in PCOS pregnant women: insights into insulin secretion and peripheral action at each trimester of gestation

Daniela Romualdi^*
, Simona De Cicco
, D Gagliano
, M Busacca
, G Campagna
, Antonio Lanzone
, Maurizio Guido

^*Autore corrispondente per questo lavoro

Facoltà di Medicina e Chirurgia "A.Gemelli"

IRCCS Oasi Maria SS. - Troina (EN)

Risultato della ricerca: Contributo in rivista › Articolo

10 Citazioni (Scopus)

Abstract

Metformin has been reported to reduce the risk of gestational diabetes (GD) in women with polycystic ovarian syndrome (PCOS). However, little is known about the mechanisms of action of this drug during pregnancy. In the attempt to fill this gap, we performed a prospective longitudinal study providing a detailed examination of glucose and insulin metabolism in pregnant women with PCOS undergoing metformin therapy.

Lingua originale	Inglese
pagine (da-a)	1477-1482
Numero di pagine	6
Rivista	Diabetes Care
Volume	36
Numero di pubblicazione	6
DOI	https://doi.org/10.2337/dc12-2071
Stato di pubblicazione	Pubblicato - 2013

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

SDG 3 Salute e benessere

All Science Journal Classification (ASJC) codes

Medicina Interna
Endocrinologia, Diabete e Metabolismo
Infermieristica Avanzata e Specializzata

Keywords

Adolescent
Adult
Female
Humans
Hypoglycemic Agents
Insulin
Metformin
Polycystic Ovary Syndrome
Pregnancy
Pregnancy Trimesters
Prospective Studies
Young Adult

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10.2337/dc12-2071

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abstract = "Metformin has been reported to reduce the risk of gestational diabetes (GD) in women with polycystic ovarian syndrome (PCOS). However, little is known about the mechanisms of action of this drug during pregnancy. In the attempt to fill this gap, we performed a prospective longitudinal study providing a detailed examination of glucose and insulin metabolism in pregnant women with PCOS undergoing metformin therapy.",

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AU - De Cicco, Simona

AU - Gagliano, D

AU - Busacca, M

AU - Campagna, G

AU - Lanzone, Antonio

AU - Guido, Maurizio

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How metformin acts in PCOS pregnant women: insights into insulin secretion and peripheral action at each trimester of gestation

Abstract

OSS delle Nazioni Unite

All Science Journal Classification (ASJC) codes

Keywords

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