How metformin acts in PCOS pregnant women: insights into insulin secretion and peripheral action at each trimester of gestation

Antonio Lanzone, Daniela Romualdi, Simona De Cicco, Maurizio Guido

Risultato della ricerca: Contributo in rivistaArticolo in rivista

10 Citazioni (Scopus)

Abstract

Metformin has been reported to reduce the risk of gestational diabetes (GD) in women with polycystic ovarian syndrome (PCOS). However, little is known about the mechanisms of action of this drug during pregnancy. In the attempt to fill this gap, we performed a prospective longitudinal study providing a detailed examination of glucose and insulin metabolism in pregnant women with PCOS undergoing metformin therapy.
Lingua originaleEnglish
pagine (da-a)1477-1482
Numero di pagine6
RivistaDiabetes Care
Volume36
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • Adolescent
  • Adult
  • Female
  • Humans
  • Hypoglycemic Agents
  • Insulin
  • Metformin
  • Polycystic Ovary Syndrome
  • Pregnancy
  • Pregnancy Trimesters
  • Prospective Studies
  • Young Adult

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