TY - JOUR
T1 - House dust mite allergy in Italy. Diagnostic and clinical relevance of Der p 23 (and of minor allergens): A real life, multicenter study
AU - Celi, Giorgio
AU - Brusca, Ignazio
AU - Scala, Enrico
AU - Villalta, Danilo
AU - Pastorello, Elide
AU - Farioli, Laura
AU - Cortellini, Gabriele
AU - Deleonardi, Gaia
AU - Galati, Pietro
AU - Losappio, Laura
AU - Manzotti, Giuseppina
AU - Pirovano, Barbara
AU - Muratore, Lionello
AU - Murzilli, Francesco
AU - Cucinelli, Francesco
AU - Musarra, Antonino
AU - Cilia, Marcello
AU - Nucera, Eleonora
AU - Aruanno, Arianna
AU - Ria, Francesco
AU - Patria, Maria Francesca
AU - Varin, Elena
AU - Polillo, Battista Roberto
AU - Sargentini, Vittorio
AU - Quercia, Oliviero
AU - Gabriela Uasuf, Carina
AU - Zampogna, Stefania
AU - Carollo, Michela
AU - Graci, Stefania
AU - Amato, Stefano
AU - Mistrello, Gianni
AU - Asero, Riccardo
PY - 2019
Y1 - 2019
N2 - House dust mites (HDM) area major cause of respiratory allergy and of perennial asthmaworldwide. 32 allergens for Dermatophagoidesfarinae(D2) and 21 for Dermatophagoides pteronyssinus(D1) have been detectedso farand novel allergens are still being reported(1). Der p 23, a gut-derived peritrophin present in the outer membrane of mite feces (2),has been recognized as a major allergen (2,3).Der p 1, Der p 2, Der p 23, and Der p 10(tropomyosin)are theonly allergens currently available for the component-resolved diagnosis of HDMallergyon ImmunoCAP.The clinical relevance of Der p 23 is only partially defined, and the prevalence and relevance of the exclusive sensitization to allergensother than groups1, 2, 10, and 23 has received little attention so far. We addressed these aspects ina large multicenter study.
AB - House dust mites (HDM) area major cause of respiratory allergy and of perennial asthmaworldwide. 32 allergens for Dermatophagoidesfarinae(D2) and 21 for Dermatophagoides pteronyssinus(D1) have been detectedso farand novel allergens are still being reported(1). Der p 23, a gut-derived peritrophin present in the outer membrane of mite feces (2),has been recognized as a major allergen (2,3).Der p 1, Der p 2, Der p 23, and Der p 10(tropomyosin)are theonly allergens currently available for the component-resolved diagnosis of HDMallergyon ImmunoCAP.The clinical relevance of Der p 23 is only partially defined, and the prevalence and relevance of the exclusive sensitization to allergensother than groups1, 2, 10, and 23 has received little attention so far. We addressed these aspects ina large multicenter study.
KW - Asthma
KW - Component resolved diagnosis
KW - Der p23
KW - House Dust Mites
KW - Respiratory allergy
KW - Asthma
KW - Component resolved diagnosis
KW - Der p23
KW - House Dust Mites
KW - Respiratory allergy
UR - http://hdl.handle.net/10807/133823
U2 - 10.1111/all.13776
DO - 10.1111/all.13776
M3 - Article
SN - 0105-4538
SP - N/A-N/A
JO - ALLERGY
JF - ALLERGY
ER -