House dust mite allergy in Italy. Diagnostic and clinical relevance of Der p 23 (and of minor allergens): A real life, multicenter study

Eleonora Nucera, Francesco Ria, Giorgio Celi, Ignazio Brusca, Enrico Scala, Danilo Villalta, Elide Pastorello, Laura Farioli, Gabriele Cortellini, Gaia Deleonardi, Pietro Galati, Laura Losappio, Giuseppina Manzotti, Barbara Pirovano, Lionello Muratore, Francesco Murzilli, Francesco Cucinelli, Antonino Musarra, Marcello Cilia, Maria Francesca PatriaElena Varin, Battista Roberto Polillo, Vittorio Sargentini, Oliviero Quercia, Carina Gabriela Uasuf, Stefania Zampogna, Michela Carollo, Stefania Graci, Stefano Amato, Gianni Mistrello, Riccardo Asero

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)

Abstract

House dust mites (HDM) area major cause of respiratory allergy and of perennial asthmaworldwide. 32 allergens for Dermatophagoidesfarinae(D2) and 21 for Dermatophagoides pteronyssinus(D1) have been detectedso farand novel allergens are still being reported(1). Der p 23, a gut-derived peritrophin present in the outer membrane of mite feces (2),has been recognized as a major allergen (2,3).Der p 1, Der p 2, Der p 23, and Der p 10(tropomyosin)are theonly allergens currently available for the component-resolved diagnosis of HDMallergyon ImmunoCAP.The clinical relevance of Der p 23 is only partially defined, and the prevalence and relevance of the exclusive sensitization to allergensother than groups1, 2, 10, and 23 has received little attention so far. We addressed these aspects ina large multicenter study.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaALLERGY
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • Asthma
  • Component resolved diagnosis
  • Der p23
  • House Dust Mites
  • Respiratory allergy

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