HLA class II allele analysis in MuSK-positive myasthenia gravis suggests a role for DQ5.

Emanuela Bartoccioni; Flavia Scuderi; A. Augugliaro; Mariapaola Marino; Amelia Evoli Stampanoni-B

doi:10.1212/01.wnl.0000339103.08830.86

HLA class II allele analysis in MuSK-positive myasthenia gravis suggests a role for DQ5.

Emanuela Bartoccioni
, Flavia Scuderi
, A. Augugliaro
, Mariapaola Marino
, Amelia Evoli Stampanoni-B

Risultato della ricerca: Contributo in rivista › Articolo

65 Citazioni (Scopus)

Abstract

We evaluated HLA-DRB1*, DQA1*, and DQB1* allele profile in MuSK-MG in comparison with a control population and non-thymoma early onset AChR-MG (AChR-EOMG). We confirm the strong positive association of AChR-EOMG with DRB1*03 DQA1*0501 and DQB1*0201 alleles as previously reported. MuSK-MG appears to be strongly associated with DRB1*16 and DQB1*0502 alleles.

Lingua originale	Inglese
pagine (da-a)	195-197
Numero di pagine	3
Rivista	Neurology
Volume	2009
DOI	https://doi.org/10.1212/01.wnl.0000339103.08830.86
Stato di pubblicazione	Pubblicato - 2009

Keywords

MHC
MuSK
myasthenia gravis

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10.1212/01.wnl.0000339103.08830.86

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title = "HLA class II allele analysis in MuSK-positive myasthenia gravis suggests a role for DQ5.",

abstract = "We evaluated HLA-DRB1*, DQA1*, and DQB1* allele profile in MuSK-MG in comparison with a control population and non-thymoma early onset AChR-MG (AChR-EOMG). We confirm the strong positive association of AChR-EOMG with DRB1*03 DQA1*0501 and DQB1*0201 alleles as previously reported. MuSK-MG appears to be strongly associated with DRB1*16 and DQB1*0502 alleles.",

keywords = "MHC, MuSK, myasthenia gravis, MHC, MuSK, myasthenia gravis",

author = "Emanuela Bartoccioni and Flavia Scuderi and A. Augugliaro and Mariapaola Marino and \{Evoli Stampanoni-B\}, Amelia",

year = "2009",

doi = "10.1212/01.wnl.0000339103.08830.86",

language = "English",

volume = "2009",

pages = "195--197",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

T1 - HLA class II allele analysis in MuSK-positive myasthenia gravis suggests a role for DQ5.

AU - Bartoccioni, Emanuela

AU - Scuderi, Flavia

AU - Augugliaro, A.

AU - Marino, Mariapaola

AU - Evoli Stampanoni-B, Amelia

PY - 2009

Y1 - 2009

N2 - We evaluated HLA-DRB1*, DQA1*, and DQB1* allele profile in MuSK-MG in comparison with a control population and non-thymoma early onset AChR-MG (AChR-EOMG). We confirm the strong positive association of AChR-EOMG with DRB1*03 DQA1*0501 and DQB1*0201 alleles as previously reported. MuSK-MG appears to be strongly associated with DRB1*16 and DQB1*0502 alleles.

AB - We evaluated HLA-DRB1*, DQA1*, and DQB1* allele profile in MuSK-MG in comparison with a control population and non-thymoma early onset AChR-MG (AChR-EOMG). We confirm the strong positive association of AChR-EOMG with DRB1*03 DQA1*0501 and DQB1*0201 alleles as previously reported. MuSK-MG appears to be strongly associated with DRB1*16 and DQB1*0502 alleles.

KW - MHC

KW - MuSK

KW - myasthenia gravis

KW - MHC

KW - MuSK

KW - myasthenia gravis

UR - http://hdl.handle.net/10807/5042

U2 - 10.1212/01.wnl.0000339103.08830.86

DO - 10.1212/01.wnl.0000339103.08830.86

M3 - Article

SN - 0028-3878

VL - 2009

SP - 195

EP - 197

JO - Neurology

JF - Neurology

ER -

HLA class II allele analysis in MuSK-positive myasthenia gravis suggests a role for DQ5.

Abstract

Keywords

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