HIV-1 A1 Subtype Epidemic in Italy Originated from Africa and Eastern Europe and Shows a High Frequency of Transmission Chains Involving Intravenous Drug Users

Andrea De Luca, Alessia Lai, Giorgio Bozzi, Marco Franzetti, Francesca Binda, Francesco R. Simonetti, Valeria Micheli, Paola Meraviglia, Patrizia Bagnarelli, Antonio Di Biagio, Laura Monno, Francesco Saladini, Maurizio Zazzi, Gianguglielmo Zehender, Massimo Ciccozzi, Claudia Balotta

Risultato della ricerca: Contributo in rivistaArticolo in rivista

14 Citazioni (Scopus)

Abstract

Subtype A accounts for only 12% of HIV-1 infections worldwide but predominates in Russia and Former Soviet Union countries of Eastern Europe. After an early propagation via heterosexual contacts, this variant spread explosively among intravenous drug users. A distinct A1 variant predominates in Greece and Albania, which penetrated directly from Africa. Clade A1 accounts for 12.5% of non-B subtypes in Italy, being the most frequent after F1 subtype.
Lingua originaleEnglish
pagine (da-a)e0146097-e0146097
RivistaPLoS One
Volume11
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • DRUG
  • HIV

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