High prevalence of hepatitis B virus infection in B-cell non-Hodgkin's lymphoma.

  • Fabrizio Marcucci
  • , Alfonso Mele
  • , Enea Spada
  • , Angela Candido
  • , Elvira Bianco
  • , Alessandro Pulsoni
  • , Paola Chionne
  • , Elisabetta Madonna
  • , Rodolfo Cotichini
  • , Anna Barbui
  • , Amalia De Renzo
  • , Fausto Dore
  • , Emilio Iannitto
  • , Vincenzo Liso
  • , Bruno Martino
  • , Marco Montanaro
  • , Livio Pagano
  • , Pellegrino Musto
  • , Maria Rapicetta

Risultato della ricerca: Contributo in rivistaArticolo

120 Citazioni (Scopus)

Abstract

In this hospital-based, multicenter case-control study we investigated the prevalence of hepatitis B virus (HBV)-related markers and HBV/hepatitis C virus (HCV) co-infection among B-cell non-Hodgkin’s lymphoma (B-NHL) cases and controls. Four hundred newly diagnosed B-NHL cases and 392 controls from other departments of the same hospitals were studied. The prevalence of positivity for hepatitis B surface antigen (HBsAg) was 8.5% among B-NHL cases and 2.8% among controls (adjusted odds ratio, 3.67; 95% confidence interval, 1.75-7.66). HBV/HCV co-infection was found in four cases, but in no controls. The finding of a positive association between HBV infection and BNHL raises the possibility that HBV may play an etiologic role in the induction of B-NHL.
Lingua originaleInglese
pagine (da-a)554-557
Numero di pagine4
RivistaHaematologica
Stato di pubblicazionePubblicato - 2006

Keywords

  • hepatitis B
  • lymphoma

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