Abstract
In this hospital-based, multicenter case-control study we investigated the prevalence of
hepatitis B virus (HBV)-related markers and HBV/hepatitis C virus (HCV) co-infection
among B-cell non-Hodgkin’s lymphoma (B-NHL) cases and controls. Four hundred newly
diagnosed B-NHL cases and 392 controls from other departments of the same hospitals
were studied. The prevalence of positivity for hepatitis B surface antigen (HBsAg)
was 8.5% among B-NHL cases and 2.8% among controls (adjusted odds ratio, 3.67;
95% confidence interval, 1.75-7.66). HBV/HCV co-infection was found in four cases,
but in no controls. The finding of a positive association between HBV infection and BNHL
raises the possibility that HBV may play an etiologic role in the induction of B-NHL.
Lingua originale | English |
---|---|
pagine (da-a) | 554-557 |
Numero di pagine | 4 |
Rivista | Haematologica |
Stato di pubblicazione | Pubblicato - 2006 |
Keywords
- hepatitis B
- lymphoma