High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria

Gennaro De Pascale; Luca Montini; Mariano Alberto Pennisi; Valentina Bernini; Riccardo Maviglia; Giuseppe Bello; Teresa Spanu; Mario Tumbarello; Massimo Antonelli

doi:10.1186/cc13858

High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria

Gennaro De Pascale
, Luca Montini
, Mariano Alberto Pennisi
, Valentina Bernini
, Riccardo Maviglia
, Giuseppe Bello
, Teresa Spanu
, Mario Tumbarello
, Massimo Antonelli

Risultato della ricerca: Contributo in rivista › Articolo

135 Citazioni (Scopus)

Abstract

The high incidence of multidrug-resistant (MDR) bacteria among patients admitted to ICUs has determined an increase of tigecycline (TGC) use for the treatment of severe infections. Many concerns have been raised about the efficacy of this molecule and increased dosages have been proposed. Our purpose is to investigate TGC safety and efficacy at higher than standard doses.

Lingua originale	Inglese
pagine (da-a)	R90-R90
Numero di pagine	9
Rivista	Critical Care
Volume	18
Numero di pubblicazione	3
DOI	https://doi.org/10.1186/cc13858
Stato di pubblicazione	Pubblicato - 2014

All Science Journal Classification (ASJC) codes

Terapia Intensiva e Rianimazione

Keywords

tygecicline

Accesso al documento

10.1186/cc13858

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abstract = "The high incidence of multidrug-resistant (MDR) bacteria among patients admitted to ICUs has determined an increase of tigecycline (TGC) use for the treatment of severe infections. Many concerns have been raised about the efficacy of this molecule and increased dosages have been proposed. Our purpose is to investigate TGC safety and efficacy at higher than standard doses.",

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AU - De Pascale, Gennaro

AU - Montini, Luca

AU - Pennisi, Mariano Alberto

AU - Bernini, Valentina

AU - Maviglia, Riccardo

AU - Bello, Giuseppe

AU - Spanu, Teresa

AU - Tumbarello, Mario

AU - Antonelli, Massimo

PY - 2014

Y1 - 2014

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AB - The high incidence of multidrug-resistant (MDR) bacteria among patients admitted to ICUs has determined an increase of tigecycline (TGC) use for the treatment of severe infections. Many concerns have been raised about the efficacy of this molecule and increased dosages have been proposed. Our purpose is to investigate TGC safety and efficacy at higher than standard doses.

KW - tygecicline

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JO - Critical Care

JF - Critical Care

IS - 3

ER -

High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria

Abstract

All Science Journal Classification (ASJC) codes

Keywords

Accesso al documento

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