HER2 immunohistochemical assessment with A0485 polyclonal antibody: is it time to refine the scoring criteria for the "2+" category?

Ilaria Pennacchia; Fabio Maria Vecchio; Arnaldo Carbone; Vincenzo Arena

doi:10.1097/PAI.0000000000000047

HER2 immunohistochemical assessment with A0485 polyclonal antibody: is it time to refine the scoring criteria for the "2+" category?

Ilaria Pennacchia, Fabio Maria Vecchio, Arnaldo Carbone, Vincenzo Arena

Facoltà di Medicina e Chirurgia "A.Gemelli"

Risultato della ricerca: Contributo in rivista › Articolo in rivista

5 Citazioni (Scopus)

Abstract

An accurate determination of human epidermal growth factor receptor 2 (Her2) status in women with breast cancer is mandatory to identify patients who will benefit from trastuzumab-based therapy.

Lingua originale	English
pagine (da-a)	31-35
Numero di pagine	5
Rivista	Applied Immunohistochemistry and Molecular Morphology
Volume	23
DOI	https://doi.org/10.1097/PAI.0000000000000047
Stato di pubblicazione	Pubblicato - 2015

Keywords

Adult
Aged
Aged, 80 and over
Antibodies
Antibodies, Monoclonal, Humanized
Antineoplastic Agents
Biomarkers, Tumor
Breast Neoplasms
Cell Membrane
Female
Humans
Immunohistochemistry
In Situ Hybridization, Fluorescence
Middle Aged
Protein Transport
Receptor, ErbB-2
Reference Standards
Research Design
Trastuzumab

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Accesso al documento

10.1097/PAI.0000000000000047

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@article{f1dbd4b7aef54cf8bb199fad1df9f094,

title = "HER2 immunohistochemical assessment with A0485 polyclonal antibody: is it time to refine the scoring criteria for the {"}2+{"} category?",

abstract = "An accurate determination of human epidermal growth factor receptor 2 (Her2) status in women with breast cancer is mandatory to identify patients who will benefit from trastuzumab-based therapy.",

keywords = "Adult, Aged, Aged, 80 and over, Antibodies, Antibodies, Monoclonal, Humanized, Antineoplastic Agents, Biomarkers, Tumor, Breast Neoplasms, Cell Membrane, Female, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Middle Aged, Protein Transport, Receptor, ErbB-2, Reference Standards, Research Design, Trastuzumab, Adult, Aged, Aged, 80 and over, Antibodies, Antibodies, Monoclonal, Humanized, Antineoplastic Agents, Biomarkers, Tumor, Breast Neoplasms, Cell Membrane, Female, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Middle Aged, Protein Transport, Receptor, ErbB-2, Reference Standards, Research Design, Trastuzumab",

author = "Ilaria Pennacchia and Vecchio, {Fabio Maria} and Arnaldo Carbone and Vincenzo Arena",

year = "2015",

doi = "10.1097/PAI.0000000000000047",

language = "English",

volume = "23",

pages = "31--35",

journal = "Applied Immunohistochemistry and Molecular Morphology",

issn = "1541-2016",

publisher = "Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320",